Novel concepts in atherogenesis: angiogenesis and hypoxia in atherosclerosis
JC Sluimer, MJ Daemen - The Journal of Pathology: A Journal …, 2009 - Wiley Online Library
The clinical complications of atherosclerosis are caused by thrombus formation, which in
turn results from rupture of an unstable atherosclerotic plaque. The formation of …
turn results from rupture of an unstable atherosclerotic plaque. The formation of …
High-resolution MR imaging of the cervical arterial wall: what the radiologist needs to know
The emergence of high-resolution rapid imaging methods has enabled magnetic resonance
(MR) imagers to noninvasively image the fine internal structure of cervical arterial walls. In …
(MR) imagers to noninvasively image the fine internal structure of cervical arterial walls. In …
Three-dimensional ultrasound quantification of intensive statin treatment of carotid atherosclerosis
This study was designed to evaluate 3-D ultrasound (3DUS)–derived vessel wall volume
(VWV), a 3-D measurement of the carotid artery intima and media, including atherosclerotic …
(VWV), a 3-D measurement of the carotid artery intima and media, including atherosclerotic …
Hemorrhage and large lipid-rich necrotic cores are independently associated with thin or ruptured fibrous caps: an in vivo 3T MRI study
H Ota, W Yu, HR Underhill, M Oikawa… - … , and vascular biology, 2009 - Am Heart Assoc
Objective—Histological studies suggest associations between hemorrhage and large lipid-
rich/necrotic cores with thin or ruptured fibrous caps in advanced atherosclerosis. We …
rich/necrotic cores with thin or ruptured fibrous caps in advanced atherosclerosis. We …
Arterial remodeling in the subclinical carotid artery disease
HR Underhill, C Yuan, VL Yarnykh, B Chu… - JACC: Cardiovascular …, 2009 - jacc.org
Objectives: We sought to identify clinical and/or plaque characteristics that affect
atherosclerotic disease progression and arterial remodeling in the carotid artery with …
atherosclerotic disease progression and arterial remodeling in the carotid artery with …
Angiogenesis as risk factor for plaque vulnerability
R Di Stefano, F Felice… - Current pharmaceutical …, 2009 - ingentaconnect.com
Atherosclerosis is now generally accepted as an inflammatory disease, characterized by
degenerative changes and extracellular accumulation of lipid and cholesterol. The evolving …
degenerative changes and extracellular accumulation of lipid and cholesterol. The evolving …
Activation of MMP8 and MMP13 by angiotensin II correlates to severe intra-plaque hemorrhages and collagen breakdown in atherosclerotic lesions with a vulnerable …
C Cheng, D Tempel, R van Haperen, L van Damme… - Atherosclerosis, 2009 - Elsevier
Angiotensin II (ATII)-mediated hypertension increases the risk for acute coronary events,
which may be caused by augmented collagen degradation. Interstitial fibers of collagen type …
which may be caused by augmented collagen degradation. Interstitial fibers of collagen type …
Cardiac magnetic resonance features of the disruption-prone and the disrupted carotid plaque
Stroke is a leading cause of long-term disability and is the third most common cause of
death in the US and western countries. Twenty percent of strokes are thought to arise from …
death in the US and western countries. Twenty percent of strokes are thought to arise from …
Enhanced expression of haemoglobin scavenger receptor in accumulated macrophages of culprit lesions in acute coronary syndromes
K Yunoki, T Naruko, R Komatsu, S Ehara… - European heart …, 2009 - academic.oup.com
Aims Effective clearance of extracellular haemoglobin (Hb) is thought to limit systemic
oxidative heme toxicity, which is presumed to contribute to the pathogenesis of plaque …
oxidative heme toxicity, which is presumed to contribute to the pathogenesis of plaque …
Hemin promotes proliferation and differentiation of endothelial progenitor cells via activation of AKT and ERK
JY Wang, YT Lee, PF Chang… - Journal of cellular …, 2009 - Wiley Online Library
Increased neovascularization is commonly observed in hemorrhagic plaques and
associated with rupture of atherosclerotic lesions. This study aims to investigate whether …
associated with rupture of atherosclerotic lesions. This study aims to investigate whether …