Cardiac cell repair therapy: a clinical perspective

BJ Gersh, RD Simari, A Behfar, CM Terzic… - Mayo Clinic …, 2009 - Elsevier
From bone marrow transplants 5 decades ago to the most recent stem cell—derived organ
transplants, regenerative medicine is increasingly recognized as an emerging core …

Electrophysiological challenges of cell-based myocardial repair

HSV Chen, C Kim, M Mercola - Circulation, 2009 - Am Heart Assoc
Cardiovascular diseases remain the major cause of death in the Western world. 1 Stem and
progenitor cell (SPC)–based therapies in animal models and human trials in recent years …

Intracoronary infusion of bone marrow-derived selected CD34+CXCR4+ cells and non-selected mononuclear cells in patients with acute STEMI and reduced left …

M Tendera, W Wojakowski, W Rużyłło… - European heart …, 2009 - academic.oup.com
Aims Comparison of intracoronary infusion of bone marrow (BM)-derived unselected
mononuclear cells (UNSEL) and selected CD34+ CXCR4+ cells (SEL) in patients with acute …

Intracoronary bone marrow cell transfer after myocardial infarction: 5-year follow-up from the randomized-controlled BOOST trial

GP Meyer, KC Wollert, J Lotz, J Pirr… - European heart …, 2009 - academic.oup.com
Aims We assessed whether a single intracoronary infusion of autologous bone marrow cells
(BMCs) can have a sustained impact on left ventricular ejection fraction (LVEF) in patients …

IFATS collection: human adipose tissue-derived stem cells induce angiogenesis and nerve sprouting following myocardial infarction, in conjunction with potent …

L Cai, BH Johnstone, TG Cook, J Tan, MC Fishbein… - Stem …, 2009 - academic.oup.com
The administration of therapeutic cell types, such as stem and progenitor cells, has gained
much interest for the limitation or repair of tissue damage caused by a variety of insults …

The BALANCE Study: clinical benefit and long-term outcome after intracoronary autologous bone marrow cell transplantation in patients with acute myocardial …

M Yousef, CM Schannwell, M Köstering, T Zeus… - Journal of the American …, 2009 - jacc.org
Objectives: The aim of this study was to investigate the quantitative amount of improvement
of ventricular hemodynamic status, geometry, and contractility as well as the long-term …

Cardiac differentiation is driven by NKX2. 5 and GATA4 nuclear translocation in tissue-specific mesenchymal stem cells

A Armiñán, C Gandía, MC Bartual… - Stem Cells and …, 2009 - liebertpub.com
Myocardial infarction is a major public health problem that causes significant mortality
despite recent advances in its prevention and treatment. Therefore, approaches based on …

Human cardiomyocyte progenitor cell transplantation preserves long-term function of the infarcted mouse myocardium

AM Smits, LW van Laake, K den Ouden… - Cardiovascular …, 2009 - academic.oup.com
Aims Recent clinical studies revealed that positive results of cell transplantation on cardiac
function are limited to the short-and mid-term restoration phase following myocardial …

Long-term results after intracoronary injection of autologous mononuclear bone marrow cells in acute myocardial infarction: the ASTAMI randomised, controlled study

JO Beitnes, E Hopp, K Lunde, S Solheim, H Arnesen… - Heart, 2009 - heart.bmj.com
Objective: To investigate long-term safety and efficacy after intracoronary injection of
autologous mononuclear bone marrow cells (mBMCs) in acute myocardial infarction (AMI) …

Long-term myocardial functional improvement after autologous bone marrow mononuclear cells transplantation in patients with ST-segment elevation myocardial …

F Cao, D Sun, C Li, K Narsinh, L Zhao, X Li… - European heart …, 2009 - academic.oup.com
Aims To evaluate the safety profile and efficacy of bone marrow mononuclear cells
(BMMNC) transplantation for ST-segment elevation myocardial infarction (STEMI) by …