Sustained Hedgehog (HH) signaling is implicated in basal cell carcinoma of the skin and
other types of cancer. Here we show that GLI1 and GLI2, the main transcriptional activators …

The reliable detection of circulating tumor cells (CTCs) in metastatic breast cancer (MBC) is
possible by using immunomagnetic separation and subsequent characterization with the …

Background Although microarray technology has become the most common method for
studying global gene expression, a plethora of technical factors across the experiment …

the⁇ MyHC gene is only highly expressed in the fetus and in diseased states such as overt
cardiac hypertrophy, heart failure and diabetes; the⁇ MyHC gene is highly expressed shortly …

随着人类基因组计划的深入, 从基因组微观分子水平研究疾病已经日趋成熟.
在基因组的构造解析己完成的基础上进一步对基因功能进行解析, 即mRNA …

The use of microarrays for cancer diagnosis implies the complex task of analyzing tens of
thousands of genomic expression data. The need for reliable, interpretable and transferable …

Many techniques of molecular biology have already been successfully ap plied in medicine.
It seems that in the nearest future, DNA microarrays can also become a useful tool in …

Branchio-oto-renal syndrome (BOR) is an autosomal dominant developmental disorder
characterized by hearing loss, branchial arch defects, and renal anomalies. Recently, eight …

Background: Although microarray technology has become the most common method for
studying global gene expression, a plethora of technical factors across the experiment …