Protein S is an anticoagulant cofactor of full-length tissue factor pathway inhibitor (TFPI) that
facilitates optimal factor Xa-inhibition and efficient down-regulation of thrombin generation in …

In the last decades evidence was obtained that protein S not only acts as cofactor of
activated protein C (APC) in the downregulation of coagulation, but also expresses …

Protein S (ProS) is a blood anticoagulant encoded by the Pros1 gene, and ProS deficiencies
are associated with venous thrombosis, stroke, and autoimmunity. These associations …

Protein S (PS) is an important natural anticoagulant with potentially multiple biologic
functions. To investigate further the role of PS in vivo, we generated Pros+/− heterozygous …

INTRODUCTION: Global coagulation tests may have a better relation with phenotype in
haemophilia than traditional coagulation tests. These include the Calibrated Automated …

Assessing the clotting function inevitably brings about dilution of plasma. With the existing
techniques of thrombin generation (TG) measurement, dilution ranges from 2: 3 to 1: 8 …

The immune response to infection includes activation of the blood clotting system, leading to
extravascular fibrin deposition to limit the spread of invasive microorganisms. Some bacteria …

Protein S (PS) is a cofactor for activated protein C (APC), which inactivates coagulation
factors (F) Va and VIIIa. Deficiency of protein C or PS is associated with risk of thrombosis …

Procoagulant and anticoagulant reactions play an important role in the regulation of
thrombin formation during secondary hemostasis. Three phases can be recognized in the …

Thrombin generation has been suggested as a method to monitor treatment with factor eight
inhibitor bypassing activity (FEIBA®) or recombinant FVIIa (rFVIIa). The sensitivity of the …