A systematic review on clinical benefits of continuous administration of β-lactam antibiotics
Objective: The clinical benefits of extended infusion or continuous infusion of β-lactam
antibiotics remain controversial. We systematically reviewed the literature to determine …
antibiotics remain controversial. We systematically reviewed the literature to determine …
Antimicrobial susceptibility testing: a primer for clinicians
KM Kuper, DM Boles, JF Mohr… - … : The Journal of Human …, 2009 - Wiley Online Library
Appropriate use of antimicrobials in health care continues to be a challenge. Reliable and
reproducible antimicrobial susceptibility testing methods are necessary to provide the …
reproducible antimicrobial susceptibility testing methods are necessary to provide the …
Clinical cure of ventilator-associated pneumonia treated with piperacillin/tazobactam administered by continuous or intermittent infusion
L Lorente, A Jiménez, MM Martín, JL Iribarren… - International journal of …, 2009 - Elsevier
The standard mode of administration of piperacillin treatment is by intermittent infusion.
However, continuous infusion may be advantageous as β-lactam antibiotics exhibit time …
However, continuous infusion may be advantageous as β-lactam antibiotics exhibit time …
Population pharmacokinetics of high-dose, prolonged-infusion cefepime in adult critically ill patients with ventilator-associated pneumonia
AM Nicasio, RE Ariano, SA Zelenitsky… - Antimicrobial agents …, 2009 - Am Soc Microbiol
ABSTRACT A population pharmacokinetic model of cefepime was constructed from data
from adult critical care patients with ventilator-associated pneumonia (VAP). A total of 32 …
from adult critical care patients with ventilator-associated pneumonia (VAP). A total of 32 …
Pharmacokinetics of antibiotics or antifungal drugs in intensive care units
G Dufour, P Montravers - Current infectious disease reports, 2009 - Springer
Intensive care unit (ICU) patients present several unusual pharmacokinetic (PK)
characteristics compared with less seriously ill patients, including increased distribution …
characteristics compared with less seriously ill patients, including increased distribution …