The rapid and extensive spread of the human immunodeficiency virus (HIV) epidemic
provides a rare opportunity to witness host–pathogen co-evolution involving humans. A focal …

Genomic studies involving well‐defined multicenter cohorts of HIV‐1/AIDS covering multiple
populations have led to a greater understanding of the role of host determinants in viral …

Although cytotoxic T lymphocytes (CTLs) in people infected with human immunodeficiency
virus type 1 can potentially target multiple virus epitopes, the same few are recognized …

Studies on human immunodeficiency virus type 1 (HIV-1) diversity are critical for
understanding viral pathogenesis and the emergence of immune escape variants and for …

HLA-B* 57 is the class I allele most consistently associated with control of human
immunodeficiency virus (HIV) replication, which may be linked to the specific HIV peptides …

The advent of molecular biology has deeply impacted the study of infectious diseases and
their epidemiology in particular. However, evolutionary biology, which provides an essential …

There is an association between expression of the MHC class I molecule HLA-B27 and
protection following human infection with either HIV or HCV. In both cases, protection has …

Human immunodeficiency virus type 1 (HIV-1)-infected persons who maintain plasma viral
loads of< 50 copies RNA/ml without treatment have been termed elite controllers (EC) …

The control of human immunodeficiency virus type 1 (HIV-1) associated with particular HLA
class I alleles suggests that some CD8+ T-cell responses may be more effective than others …

Background: Current public health efforts often use molecular technologies to identify and
contain communicable disease networks, but not for HIV. Here, we investigate how …