Managing cardiovascular and renal risk: the potential of direct renin inhibition
Aliskiren is the first direct renin inhibitor for the treatment of hypertension. Clinical
experience from studies in over 14,000 patients has shown that aliskiren, alone or in …
experience from studies in over 14,000 patients has shown that aliskiren, alone or in …
RPC6 up-regulation in Ang II-induced podocyte apoptosis might result from ERK activation and NF-κB translocation
H Zhang, J Ding, Q Fan, S Liu - Experimental Biology and …, 2009 - journals.sagepub.com
Angiotensin II (Ang II) has been recognized as an apoptosis inducer in podocytes, but the
mechanism of apoptosis induced by Ang II is unclear. Transient receptor potential cation …
mechanism of apoptosis induced by Ang II is unclear. Transient receptor potential cation …
Hypertension Management and End Organ Protection: Focus on Aliskiren
T Imanishi, H Tsujioka… - Clinical Medicine …, 2009 - journals.sagepub.com
The renin-angiotensin system (RAS) activity is a key factor in the pathophysiology and
development of hypertension, atherosclerosis, heart failure, and renal disease. It is unclear …
development of hypertension, atherosclerosis, heart failure, and renal disease. It is unclear …
Defining the role of renin/angiotensin targeted antihypertensive therapy.
J Probstfield - Journal of Family Practice, 2009 - search.ebscohost.com
The article reports on a study that evaluates the effectiveness of renin-angiotensin-
aldosterone system (RAAS) to treat hypertension. It suggests selecting treatment that …
aldosterone system (RAAS) to treat hypertension. It suggests selecting treatment that …