Insulin, insulin-like growth factor-I, and risk of breast cancer in postmenopausal women

MJ Gunter, DR Hoover, H Yu… - Journal of the …, 2009 - academic.oup.com
Background The positive association between obesity and postmenopausal breast cancer
has been attributed, in part, to the fact that estrogen, a risk factor for breast cancer, is …

Monitoring of acromegaly: what should be performed when GH and IGF‐1 levels are discrepant?

PU Freda - Clinical endocrinology, 2009 - Wiley Online Library
Monitoring of a patient with acromegaly requires periodic evaluation of levels of GH and IGF‐
1, the biochemical markers of this disease. Although the results of these two tests are usually …

Dried plum, an emerging functional food that may effectively improve bone health

S Hooshmand, BH Arjmandi - Ageing Research Reviews, 2009 - Elsevier
Osteoporosis is a debilitating disorder that affects both female and male, albeit to a greater
extent in women than men. As the demographic shift to a more aged population continues, a …

Perinatal exposure to low-dose 2, 2′, 4, 4′-tetrabromodiphenyl ether affects growth in rat offspring: what is the role of IGF-1?

A Suvorov, MC Battista, L Takser - Toxicology, 2009 - Elsevier
BACKGROUND: Polybrominated diphenyl ethers (PBDEs) are a group of environmental
contaminants increasing in North America. Few data are available on their growth effects at …

Transdermal hormone therapy in postmenopausal women: a review of metabolic effects and drug delivery technologies

NW Kopper, J Gudeman… - Drug design, development …, 2009 - Taylor & Francis
Vasomotor symptoms (VMS) associated with menopause can cause significant discomfort
and decrease the quality of life for women in the peri-menopausal and post-menopausal …

Growth hormone, menopause and ageing: no definite evidence for 'rejuvenation'with growth hormone

G Fanciulli, A Delitala, G Delitala - Human reproduction update, 2009 - academic.oup.com
BACKGROUND Estrogens regulate growth hormone (GH) secretion and modulate the tissue
responsiveness to GH. After the menopause, and during ageing, a decline in GH secretion …

Efficacy of long-term lanreotide treatment in patients with acromegaly

Y Toledano, L Rot, Y Greenman, S Orlovsky, Y Pauker… - Pituitary, 2009 - Springer
We investigated the effectiveness of lanreotide for the treatment of active acromegaly in a
retrospectively multicenter case series including 53 patients (24 male, 29 female; mean age …

Short-term oral oestrogen therapy dissociates the growth hormone/insulin-like growth factor-I axis without altering energy metabolism in premenopausal women

DS Huang, AJ O'Sullivan - Growth Hormone & IGF Research, 2009 - Elsevier
OBJECTIVE: Oral oestrogen has been shown to dissociate the growth hormone (GH)/insulin-
like growth factor (IGF)-I axis and alter energy metabolism in postmenopausal women. This …

Body composition and adipokine levels in growth hormone antagonist mice

V Magon - 2009 - rave.ohiolink.edu
The study examined age-and gender-related changes in body weight, body composition (6
to 80 weeks of age), fasting blood glucose level, and plasma leptin level (8, 13, 26, 52, and …

[PDF][PDF] Factors that Affect the Dosing Regimen of Growth Hormone Replacement Therapy in Adults with Growth Hormone Deficiency

KCJ Yuen - … Journal of Biomedical and Pharmaceutical Sciences - academia.edu
Growth hormone (GH) deficiency in adulthood is now widely accepted as a distinct clinical
syndrome with significant morbidities. These include abnormal body composition, reduced …