Immunotherapeutic applications of CpG oligodeoxynucleotide TLR9 agonists
J Vollmer, AM Krieg - Advanced drug delivery reviews, 2009 - Elsevier
Toll-like receptor 9 (TLR9) agonists have demonstrated substantial potential as vaccine
adjuvants, and as mono-or combination therapies for the treatment of cancer and infectious …
adjuvants, and as mono-or combination therapies for the treatment of cancer and infectious …
Immunobiology of asthma
Q Hamid, M Tulic - Annual review of physiology, 2009 - annualreviews.org
Asthma is characterized by chronic inflammation of the airways in which there is an
overabundance of eosinophils, mast cells, and activated T helper lymphocytes. These …
overabundance of eosinophils, mast cells, and activated T helper lymphocytes. These …
Insights into the role of infection in atherogenesis and in plaque rupture
SE Epstein, J Zhu, AH Najafi, MS Burnett - Circulation, 2009 - Am Heart Assoc
(and possibly intermittent) level, or produce an abortive infection (see below). Alternatively,
they can be delivered to the vessel wall by circulating monocytes, which can be infected by …
they can be delivered to the vessel wall by circulating monocytes, which can be infected by …
Expression and function of toll like receptors in chronic lymphocytic leukaemia cells
Mature B‐cells can recognize microbial antigens via B‐cell‐receptor (BCR) in a specific way
and via Toll‐like receptors (TLR) in a costimulatory manner. A wealth of information is …
and via Toll‐like receptors (TLR) in a costimulatory manner. A wealth of information is …
Pattern recognition by Toll-like receptors
S Bauer, T Müller, S Hamm - Target Pattern Recognition in Innate …, 2009 - Springer
The mammalian immune system senses pathogens through pattern recognition receptors
and responds with activation. The Toll-like receptors (TLRs) that are expressed on antigen …
and responds with activation. The Toll-like receptors (TLRs) that are expressed on antigen …
Increased expression of Toll-like receptors 4 and 9 in human lung cancer
YB Zhang, FL He, M Fang, TF Hua, BD Hu… - Molecular biology …, 2009 - Springer
Background It has been reported lately that Toll-like receptors (TLRs) play an essential role
in the activation of innate immunity, and TLRs are expressed in a large number of immune …
in the activation of innate immunity, and TLRs are expressed in a large number of immune …
Structural characteristics and in vitro macrophage activation of acetyl fucoidan from Cladosiphon okamuranus
T Teruya, H Tatemoto, T Konishi, M Tako - Glycoconjugate journal, 2009 - Springer
We investigated a structural characteristics of acetyl fucoidan (CAF) isolated from
commercially cultured Cladosiphon okamuranus. The CAF-induced macrophage activation …
commercially cultured Cladosiphon okamuranus. The CAF-induced macrophage activation …
Toll-like receptors in multiple sclerosis
MK Racke, PD Drew - Toll-like Receptors: Roles in Infection and …, 2009 - Springer
Multiple sclerosis (MS) is a chronic disease of the central nervous system (CNS)
characterized by inflammation, demyelination, and axonal pathology. The exact causes of …
characterized by inflammation, demyelination, and axonal pathology. The exact causes of …
TLR9 signaling promotes tumor progression of human lung cancer cell in vivo
T Ren, L Xu, S Jiao, Y Wang, Y Cai, Y Liang… - Pathology & Oncology …, 2009 - Springer
Abstract Toll like receptor 9 (TLR9) was identified mainly in cells of the immune system, and
CpG oligonucleotides (CpG ODN), which induces signaling through TLR9, are currently …
CpG oligonucleotides (CpG ODN), which induces signaling through TLR9, are currently …
Mycoplasma lipoproteins and Toll-like receptors
L Zuo, Y Wu, X You - Journal of Zhejiang University Science B, 2009 - Springer
Mycoplasmas, the smallest free-living, self-replicating bacteria with diameters of 200 to 800
nm, have been reported to be associated with human diseases. It is well known that the …
nm, have been reported to be associated with human diseases. It is well known that the …