Mechanisms of muscle degeneration, regeneration, and repair in the muscular dystrophies

GQ Wallace, EM McNally - Annual review of physiology, 2009 - annualreviews.org
To withstand the rigors of contraction, muscle fibers have specialized protein complexes that
buffer against mechanical stress and a multifaceted repair system that is rapidly activated …

Sperm–egg adhesion and fusion in mammals

P Sutovsky - Expert reviews in molecular medicine, 2009 - cambridge.org
Fertilisation is an orchestrated, stepwise process during which the participating male and
female gametes undergo irreversible changes, losing some of their structural components …

Embryonic temperature affects muscle fibre recruitment in adult zebrafish: genome-wide changes in gene and microRNA expression associated with the transition …

IA Johnston, HT Lee, DJ Macqueen… - Journal of …, 2009 - journals.biologists.com
We investigated the effects of embryonic temperature (ET) treatments (22, 26 and 31° C) on
the life-time recruitment of fast myotomal muscle fibres in zebrafish Danio rerio L. reared at …

Nap1-mediated actin remodeling is essential for mammalian myoblast fusion

SJ Nowak, PC Nahirney… - Journal of cell …, 2009 - journals.biologists.com
Myoblast fusion is crucial for the formation, growth, maintenance and regeneration of healthy
skeletal muscle. Unfortunately, the molecular machinery, cell behaviors, and membrane and …

Myoferlin is critical for endocytosis in endothelial cells

PN Bernatchez, A Sharma… - American Journal of …, 2009 - journals.physiology.org
Myoferlin is a member of the ferlin family of proteins that promotes endomembrane fusion
with the plasma membrane in muscle cells and endothelial cells. In addition, myoferlin is …

While dysferlin and myoferlin are coexpressed in the human placenta, only dysferlin expression is responsive to trophoblast fusion in model systems

JM Robinson, WE Ackerman IV… - Biology of …, 2009 - academic.oup.com
The syncytiotrophoblast is a specialized epithelium derived from mononuclear
cytotrophoblasts that fuse to form this extensive syncytium. Dysferlin is expressed primarily …

Metakaryotic stem cell lineages in organogenesis of humans and other metazoans

EV Gostjeva, V Koledova, A Tomita-Mitchell… - …, 2009 - Taylor & Francis
A non-eukaryotic, metakaryotic cell with large, open mouthed, bell shaped nuclei represents
an important stem cell lineage in fetal/juvenile organogenesis in humans and rodents. Each …

Placental proteomics: a shortcut to biological insight

JM Robinson, DD Vandré, WE Ackerman IV - Placenta, 2009 - Elsevier
Proteomics analysis of biological samples has the potential to identify novel protein
expression patterns and/or changes in protein expression patterns in different …

Molecular bandages: inside-out, outside-in repair of cellular membranes. Focus on “Myoferlin is critical for endocytosis in endothelial cells”

S Cipta, HH Patel - American Journal of Physiology-Cell …, 2009 - journals.physiology.org
The plasma membrane separates the external and internal cellular environments. Many 17
processes that injure the plasma membrane are a prelude to cell death (ie, necrosis …

3rd Annual Dysferlin Conference 2–5 June 2009, Boston, Massachusetts, USA

DE Albrecht, N Garg, LE Rufibach, BA Williams… - Neuromuscular …, 2009 - Elsevier
Conclusions The Dysferlin Conference has continued to grow rapidly, in both number of
participants and breadth of research presented, since the first conference in 2007. It is …