The afferent innervation of the urinary bladder consists primarily of small myelinated (Aδ)
and unmyelinated (C-fiber) axons that respond to chemical and mechanical stimuli …

BACKGROUND: Increased nerve growth factor (NGF) levels have been reported in the
bladder tissue and urine of patients with overactive bladder and detrusor overactivity (DO) …

Aims Urinary nerve growth factor (NGF) levels have been found to be higher in patients with
overactive bladder (OAB) compared to normal controls. This study investigated the effect of …

1. BACKGROUND 2. ROLE AND IMPORTANCE OF CEREBRAL CONTROL OF VOIDING 3.
CORTICAL AND SUBCORTICAL CENTRES INVOLVED IN BLADDER CONTROL …

Cytokines are upregulated in a variety of inflammatory conditions and cytokine/receptor
interactions can activate JAK-STAT signaling. Previous studies demonstrated upregulation …

Extracellular signal-regulated kinases (ERK1 and ERK2) are phosphorylated in the nervous
system after somatic or visceral stimulation or inflammation and play roles in central …

Previous study has shown that colitis-induced increases in calcitonin gene-related peptide
(CGRP) immunoreactivity in bladder afferent neurons result in sensory cross-sensitization …

OBJECTIVE To measure urinary nerve growth factor (uNGF, essential in nerve growth and
regeneration) levels in patients with a cerebrovascular accident (CVA), to determine whether …

Neurokinins (NK) released from terminals of dorsal root ganglion (DRG) neurons may
control firing of these neurons by an autofeedback mechanism. In this study we used patch …

The lower urinary tract has two main functions:(i) storage and (ii) periodic expulsion of urine,
which are regulated by a complex neural control system in the brain and lumbosacral spinal …