Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model
Therapeutic strategies based on modulation of microRNA (miRNA) activity hold great
promise due to the ability of these small RNAs to potently influence cellular behavior. In this …
promise due to the ability of these small RNAs to potently influence cellular behavior. In this …
[HTML][HTML] Mesenchymal stem cells: emerging therapy for Duchenne muscular dystrophy
CD Markert, A Atala, JK Cann, G Christ, M Furth… - PM&R, 2009 - Elsevier
Multipotent cells that can give rise to bone, cartilage, fat, connective tissue, and skeletal and
cardiac muscle are termed mesenchymal stem cells. These cells were first identified in the …
cardiac muscle are termed mesenchymal stem cells. These cells were first identified in the …
Overexpression of Galgt2 in skeletal muscle prevents injury resulting from eccentric contractions in both mdx and wild-type mice
PT Martin, R Xu, LR Rodino-Klapac… - … of Physiology-Cell …, 2009 - journals.physiology.org
The cytotoxic T cell (CT) GalNAc transferase, or Galgt2, is a UDP-GalNAc: β1, 4-N-
acetylgalactosaminyltransferase that is localized to the neuromuscular synapse in adult …
acetylgalactosaminyltransferase that is localized to the neuromuscular synapse in adult …
Therapy for neuromuscular disorders
ALH Arnett, JR Chamberlain… - Current opinion in genetics …, 2009 - Elsevier
Research into therapeutic approaches for both recessive and dominant neuromuscular
disorders has made great progress over the past few years. In the field of gene therapy …
disorders has made great progress over the past few years. In the field of gene therapy …
[HTML][HTML] Therapeutic delivery of miR-26a inhibits cancer cell proliferation and induces tumor-specific apoptosis
J Kota, RR Chivukula, KA O'Donnell, EA Wentzel… - Cell, 2009 - ncbi.nlm.nih.gov
Therapeutic strategies based on modulation of microRNA (miRNA) activity hold great
promise due to the ability of these small RNAs to potently influence cellular behavior. In this …
promise due to the ability of these small RNAs to potently influence cellular behavior. In this …
Silencing of T lymphocytes by antigen-driven programmed death in recombinant adeno-associated virus vector–mediated gene therapy
VM Velazquez, DG Bowen… - Blood, The Journal of the …, 2009 - ashpublications.org
Recombinant adeno-associated virus (rAAV) vectors are considered promising for human
gene replacement because they facilitate stable expression of therapeutic proteins in …
gene replacement because they facilitate stable expression of therapeutic proteins in …
Systemic delivery of AAV8 in utero results in gene expression in diaphragm and limb muscle: treatment implications for muscle disorders
BM Koppanati, J Li, X Xiao, PR Clemens - Gene therapy, 2009 - nature.com
One of the major challenges in the treatment of primary muscle disorders, which often affect
many muscle groups, is achieving efficient, widespread transgene expression in muscle. In …
many muscle groups, is achieving efficient, widespread transgene expression in muscle. In …
The" Excellence in Translational Medicine" and" Bedside-to-Bench" Awards 2007–08
RJ Ablin, FM Marincola, PG Natali - Journal of Translational Medicine, 2009 - Springer
In a continuing endeavor to recognize outstanding contributions in the field of translational
medicine, the Editorial Board of the Journal of Translational Medicine (JTM) established" …
medicine, the Editorial Board of the Journal of Translational Medicine (JTM) established" …
Fibrotic pathways in the dystrophin deficient heart
A Wakefield - 2009 - research.usq.edu.au
Duchenne muscular dystrophy is the most prevalent and severe of the muscular dystrophies.
A hallmark of dystrophic muscle is fibrosis which is a result of chronic cycles of degeneration …
A hallmark of dystrophic muscle is fibrosis which is a result of chronic cycles of degeneration …
Ongoing cellular responses to transgene products encoded by recombinant adeno-associated virus (rAAV) vectors
VM Best - 2009 - rave.ohiolink.edu
Recombinant adeno-associated virus (rAAV) vectors are considered promising for human
gene replacement because they facilitate the stable expression of numerous therapeutic …
gene replacement because they facilitate the stable expression of numerous therapeutic …