Background: Some, although not all, studies report small hippocampal volume in patients
with major depressive disorder (MDD) relative to healthy controls. Here, we explore the …

Depression and suicidal behavior have recently been shown to be associated with
disturbances in structural and synaptic plasticity. Brain-derived neurotrophic factor (BDNF) …

Objective. So far, there have been no attempts to integrate the growing number of all brain
volumetric magnetic resonance imaging studies in depression. In this comprehensive meta …

Both major depressive disorder and bipolar disorder are the subject of a voluminous
imaging and genetics literature. Here, we attempt a comprehensive review of MRI and …

Its last edition hailed as" an essential volume for psychiatry residents as well as
clinicians"(Journal of Psychiatric Practice), The American Psychiatric Publishing Textbook of …

It is now well established that the mammalian brain has the capacity to produce new
neurons into adulthood. One such region that provides the proper milieu to sustain …

Exposure to interpersonal violence or abuse affects the physical and emotional well-being of
affected individuals. In particular, exposure to trauma during development increases the risk …

New neurons are continually generated in the subgranular zone of the dentate gyrus and in
the subventricular zone of the lateral ventricles of the adult brain. These neurons proliferate …

The concept of inducing convulsions, mainly through chemical means, to promote mental
wellness has existed since the 16th century. In 1938, Italian scientists first applied …

Chronic stress, by initiating changes in the hypothalamic‐pituitary‐adrenal (HPA) axis and
the immune system, acts as a trigger for anxiety and depression. There is experimental and …