Purpose To determine the incidence, outcomes, and current strategies for management of
brain metastases in patients with human epidermal growth factor receptor 2 (HER2)–positive …

There is strong clinical evidence that trastuzumab, a monoclonal antibody targeting the
human epidermal growth factor receptor (HER) two tyrosine kinase receptor, is an important …

Learning Objectives Analyze the clinical trial data for the treatment of breast cancer.
Evaluate the risk of cardiotoxicity associated with the use of trastuzumab. Design and …

BACKGROUND: One of the recent advances in the treatment of breast cancer is
trastuzumab. However, a major side effect of this medication is cardiomyopathy. Our …

Trastuzumab (Herceptin), a monoclonal antibody against HER2 has established itself as the
treatment paradigm of HER2-overexpressing breast cancer. Its success, however, has been …

Targeted therapy against cancer shows not only promise, but also limits. No matter how
specific the target, many pathways and cell types can be affected, some unexpectedly. A …

Amerykańskie Towarzystwo Kardiologiczne (AHA) w swoim najnowszym dokumencie
dotyczącym prewencji rozwoju niewydolności serca uznało antracykliny za jeden z …

A feasibility-phase II study was conducted to assess the cardiotoxicity of weekly
trastuzumab, epirubicin, and paclitaxel in patients with human epidermal growth factor …

Nas últimas décadas, o advento de estratégias de tratamento para diversos tipos de
tumores permitiu aos pacientes oncológicos longa sobrevida, possibilitando o …

Agrīno stadiju krūts vēža pacientēm pēc krūti saudzējošās ārstēšanas ir prognozējama liela
dzīvildze, kuras laikā var manifistēties staru terapijas komplikācijas. Darba mērķis bija …