The discovery of cannabinoid receptors and subsequent identification of their endogenous
ligands (endocannabinoids) in early 1990s have greatly accelerated research on …

The therapeutic potential of cannabinoids has been the topic of extensive investigation
following the discovery of cannabinoid receptors and their endogenous ligands …

The management of psychosis in Parkinson's disease (PD) has been considered a great
challenge for clinicians and there is a need for new pharmacological intervention. Previously …

The cannabinoid receptor 1 (CB 1) and CB 2 cannabinoid receptors, associated with drugs
of abuse, may provide a means to treat pain, mood, and addiction disorders affecting …

The endocannabinoid signaling system (eCBSS) is composed of cannabinoid (CB)
receptors, their endogenous ligands (the endocannabinoids, eCB) and the enzymes that …

Gap junctions play an important role in brain physiology. They synchronize neuronal activity
and connect glial cells participating in the regulation of brain metabolism and homeostasis …

Endocannabinoids are lipid mediators with protective effects in many diseases of the
nervous system. We have studied the modulation of the endocannabinoid system after a …

One of the Most Rapidly Advancing Fields in Modern Neuroscience The success of
molecular biology and the new tools derived from molecular genetics have revolutionized …

Discovery of the endogenous cannabinoid and N‐acyl amide, anandamide (N‐arachidonoyl
ethanolamine), paved the way for lipidomics discoveries in the growing family of N‐acyl …

Cannabinoids produce a plethora of biological effects, including the modulation of neuronal
activity through the activation of CB1 receptors and of immune responses through the …