Immunological memory provides the basis for successful vaccines. It is important to
understand the properties of memory cells. There is much known about the phenotype and …

The failure of the inactivated Chlamydia-based vaccine trials in the 1960s has led
researchers studying Chlamydia to take cautious and rational approaches to develop safe …

Infection with the obligate intracellular bacterium Chlamydia trachomatis is controlled
primarily by IFN-γ and Th1 immunity. In this study, we used cells from a Chlamydia-specific …

Vaccines are needed to prevent the oculogenital diseases of Chlamydia trachomatis.
Infected hosts develop immunity, although temporary, and experimental vaccines have …

Using a combination of affinity chromatography and tandem mass spectrometry, we recently
identified 8 MHC class II (IA b)-bound Chlamydia peptides eluted from dendritic cells (DCs) …

Chlamydia trachomatis is a Gram-negative obligate intracellular pathogen that remains the
leading cause of bacterial sexually transmitted disease worldwide, despite the availability of …

Mice deficient in B cells (µmT mice) were used to evaluate the role of antibody in enhanced
chlamydial clearance and reduction of pathology afforded by vaccination with recombinant …

A secreted chlamydial protease designated CPAF (Chlamydial Protease/proteasome-like
Activity Factor) degrades host proteins, enabling Chlamydia to evade host defenses and …

衣原体为专性胞内寄生菌, 具有广泛致病谱, 是重要的致病菌. γ 干扰素在抗衣原体感染中起重要
作用, 其介导的抗衣原体感染效应机制包括耗竭色氨酸, 诱导铁缺失途径以及激活一氧化氮合酶 …

Using a combination of affinity chromatography and tandem mass spectrometry, we recently
identified 8 MHC class II (IA b)-bound Chlamydia peptides eluted from dendritic cells (DCs) …