Inflammation in chronic kidney disease: role in the progression of renal and cardiovascular disease

DM Silverstein - Pediatric nephrology, 2009 - Springer
Inflammation is the response of the vasculature or tissues to various stimuli. An acute and
chronic pro-inflammatory state exists in patients with chronic kidney disease (CKD) …

Persistent inflammation as a catalyst for other risk factors in chronic kidney disease: a hypothesis proposal

JJ Carrero, P Stenvinkel - Clinical Journal of the American Society …, 2009 - journals.lww.com
Because inflammation by now is a “traditional” finding that predicts poor outcome and
cardiovascular events in the vast majority of patients with ESRD, it could be argued that …

Association of serum phosphate with vascular and valvular calcification in moderate CKD

KL Adeney, DS Siscovick, JH Ix… - Journal of the …, 2009 - journals.lww.com
Within the normal range, higher serum phosphate concentrations are associated with
cardiovascular events and mortality in individuals with chronic kidney disease (CKD) and in …

Peripheral vascular calcification in long-haemodialysis patients: associated factors and survival consequences

G Jean, E Bresson, JC Terrat, T Vanel… - Nephrology Dialysis …, 2009 - academic.oup.com
Abstract Background. Vascular calcifications (VCs) are frequently observed in chronic
kidney disease (CKD) and haemodialysis (HD) patients. They have been associated with …

Fetuin-A protects against atherosclerotic calcification in CKD

R Westenfeld, C Scha, T Kru, C Haarmann… - Journal of the …, 2009 - journals.lww.com
Reduced serum levels of the calcification inhibitor fetuin-A associate with increased
cardiovascular mortality in dialysis patients. Fetuin-A–deficient mice display calcification of …

[HTML][HTML] Fully phosphorylated fetuin-A forms a mineral complex in the serum of rats with adenine-induced renal failure

I Matsui, T Hamano, S Mikami, N Fujii, Y Takabatake… - Kidney international, 2009 - Elsevier
The serum glycoprotein fetuin-A is an important inhibitor of extra-osseous calcification, but
correlations between serum fetuin-A levels and the extent of vascular calcification are …

Progression of coronary artery calcification in renal transplantation and the role of secondary hyperparathyroidism and inflammation

S Mazzaferro, M Pasquali, F Taggi… - Clinical Journal of the …, 2009 - journals.lww.com
Progression of Coronary Artery Calcification in Renal Transp... : Clinical Journal of the
American Society of Nephrology Progression of Coronary Artery Calcification in Renal …

Characterization of granulations of calcium and apatite in serum as pleomorphic mineralo-protein complexes and as precursors of putative nanobacteria

JD Young, J Martel, D Young, A Young, CM Hung… - PLoS one, 2009 - journals.plos.org
Calcium and apatite granulations are demonstrated here to form in both human and fetal
bovine serum in response to the simple addition of either calcium or phosphate, or a …

Association of fetuin-A levels with the progression of aortic valve calcification in non-dialyzed patients

R Koos, V Brandenburg, AH Mahnken… - European heart …, 2009 - academic.oup.com
Aims Fetuin-A has been identified as a potent circulating inhibitor of ectopic calcification. We
investigated the relationship between baseline fetuin-A serum levels and the rate of …

The pathogenesis of vascular calcification in the chronic kidney disease mineral bone disorder: the links between bone and the vasculature

KA Hruska, S Mathew, RJ Lund, I Memon… - Seminars in nephrology, 2009 - Elsevier
Considerable scientific progress in the pathogenesis of vascular calcification that has
accrued in recent years is reviewed in this article. Factors regulating mesenchymal cell …