How mitochondria produce reactive oxygen species
MP Murphy - Biochemical journal, 2009 - portlandpress.com
The production of ROS (reactive oxygen species) by mammalian mitochondria is important
because it underlies oxidative damage in many pathologies and contributes to retrograde …
because it underlies oxidative damage in many pathologies and contributes to retrograde …
The Randle cycle revisited: a new head for an old hat
L Hue, H Taegtmeyer - American Journal of Physiology …, 2009 - journals.physiology.org
In 1963, Lancet published a paper by Randle et al. that proposed a “glucose-fatty acid cycle”
to describe fuel flux between and fuel selection by tissues. The original biochemical …
to describe fuel flux between and fuel selection by tissues. The original biochemical …
Involvement of the vitamin D receptor in energy metabolism: regulation of uncoupling proteins
KE Wong, FL Szeto, W Zhang, H Ye… - American journal …, 2009 - journals.physiology.org
Recent studies have established that vitamin D plays multiple biological roles beyond
calcium metabolism; however, whether vitamin D is involved in energy metabolism is …
calcium metabolism; however, whether vitamin D is involved in energy metabolism is …
[HTML][HTML] L-carnitine decreases DNA damage and improves the in vitro blastocyst development rate in mouse embryos
OBJECTIVE: To optimize the L-carnitine (LC) concentration as a supplement in embryo
culture medium and to investigate the effect of LC on developing embryos. DESIGN …
culture medium and to investigate the effect of LC on developing embryos. DESIGN …
[HTML][HTML] Daily injection of tumor necrosis factor-α increases hepatic triglycerides and alters transcript abundance of metabolic genes in lactating dairy cattle
BJ Bradford, LK Mamedova, JE Minton… - The Journal of …, 2009 - Elsevier
To determine whether inflammation can induce bovine fatty liver, we administered
recombinant bovine tumor necrosis factor-α (rbTNF) to late-lactation Holstein cows. Cows …
recombinant bovine tumor necrosis factor-α (rbTNF) to late-lactation Holstein cows. Cows …
The paradox of the carnitine palmitoyltransferase type Ia P479L variant in Canadian Aboriginal populations
CR Greenberg, LA Dilling, GR Thompson… - Molecular genetics and …, 2009 - Elsevier
Investigation of seven patients from three families suspected of a fatty acid oxidation defect
showed mean CPT-I enzyme activity of 5.9±4.9 percent of normal controls. The families, two …
showed mean CPT-I enzyme activity of 5.9±4.9 percent of normal controls. The families, two …
An overview of beta-oxidation disorders.
Fatty acids (FAs) are components of cell membrane, enzymes, and hormones and are one of
the most important energy sources for many organisms. There are several types of fatty-acid …
the most important energy sources for many organisms. There are several types of fatty-acid …
Hypermetabolism, hyperphagia, and reduced adiposity in tankyrase-deficient mice
TYJ Yeh, KK Beiswenger, P Li, KE Bolin, RM Lee… - Diabetes, 2009 - Am Diabetes Assoc
OBJECTIVE Tankyrase (TNKS) is a Golgi-associated poly-ADP-ribose polymerase that is
implicated in the regulation of GLUT4 trafficking in 3T3-L1 adipocytes. Its chromosomal …
implicated in the regulation of GLUT4 trafficking in 3T3-L1 adipocytes. Its chromosomal …
Muscle acylcarnitines during short-term fasting in lean healthy men
MR Soeters, HP Sauerwein, M Duran… - Clinical …, 2009 - portlandpress.com
The transition from the fed to the fasted resting state is characterized by, among other things,
changes in lipid metabolism and peripheral insulin resistance. Acylcarnitines have been …
changes in lipid metabolism and peripheral insulin resistance. Acylcarnitines have been …
3,5-Diiodo-l-thyronine rapidly enhances mitochondrial fatty acid oxidation rate and thermogenesis in rat skeletal muscle: AMP-activated protein kinase involvement
A Lombardi, P de Lange, E Silvestri… - American Journal …, 2009 - journals.physiology.org
Triiodothyronine regulates energy metabolism and thermogenesis. Among triiodothyronine
derivatives, 3, 5-diiodo-l-thyronine (T2) has been shown to exert marked effects on energy …
derivatives, 3, 5-diiodo-l-thyronine (T2) has been shown to exert marked effects on energy …