Photodynamic therapy (PDT) is a treatment modality for cancer and various other diseases.
The clinical protocol covers the illumination of target cells (or tissue), which have been …

The study of biological systems in their real environmental conditions is crucial to decipher
the true image of structures and processes underlying their functionality. In this regard …

Although the oral cavity is easily accessible to inspection, patients with oral cancer most
often present at a late stage, leading to high morbidity and mortality. Autofluorescence …

In this work, we report the application of novel, water-soluble fluorescent Ag clusters in
fluorescent sensors for detecting cysteine, an important biological analyte. The fluorescence …

Methods of optical spectroscopy that provide quantitative, physically or physiologically
meaningful measures of tissue properties are an attractive tool for the study, diagnosis …

Confocal endomicroscopes aim at providing to the clinician microscopic imaging of a living
tissue. The currently available microendoscopic devices use the principle of confocal …

A compact clinically compatible fluorescence lifetime imaging microscopy (FLIM) system
was designed and built for intraoperative disease diagnosis and validated in vivo in a …

Two nanocrystal-osmium (II) polypyridyl (NC-Os (II) PP) conjugates have been designed to
detect oxygen in biological environments. Polypyridines appended with a single free amine …

OBJECTIVE: Plaque with dense inflammatory cells, including macrophages, thin fibrous cap
and superficial necrotic/lipid core is thought to be prone-to-rupture. We report a time …

The feasibility of using quantitative diffuse reflectance spectroscopy to longitudinally monitor
physiological response to cancer therapy was evaluated in a preclinical model. This study …