Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases
DB Kell - BMC medical genomics, 2009 - Springer
Background The production of peroxide and superoxide is an inevitable consequence of
aerobic metabolism, and while these particular'reactive oxygen species'(ROSs) can exhibit a …
aerobic metabolism, and while these particular'reactive oxygen species'(ROSs) can exhibit a …
Is drug release necessary for antimicrobial activity of siderophore-drug conjugates? Syntheses and biological studies of the naturally occurring salmycin “Trojan Horse …
The recent rise in drug resistance found amongst community acquired infections has
sparked renewed interest in developing antimicrobial agents that target resistant organisms …
sparked renewed interest in developing antimicrobial agents that target resistant organisms …
Three Genomes from the Phylum Acidobacteria Provide Insight into the Lifestyles of These Microorganisms in Soils
NL Ward, JF Challacombe, PH Janssen… - Applied and …, 2009 - Am Soc Microbiol
The complete genomes of three strains from the phylum Acidobacteria were compared.
Phylogenetic analysis placed them as a unique phylum. They share genomic traits with …
Phylogenetic analysis placed them as a unique phylum. They share genomic traits with …
Siderophores as drug delivery agents: application of the “Trojan Horse” strategy
U Möllmann, L Heinisch, A Bauernfeind, T Köhler… - Biometals, 2009 - Springer
The outer membrane permeability barrier is an important resistance factor of bacterial
pathogens. In combination with drug inactivating enzymes, target alteration and efflux, it can …
pathogens. In combination with drug inactivating enzymes, target alteration and efflux, it can …
Iron dynamics in the rhizosphere as a case study for analyzing interactions between soils, plants and microbes
Iron is an essential element for plants and microbes. However, in most cultivated soils, the
concentration of iron available for these living organisms is very low because its solubility is …
concentration of iron available for these living organisms is very low because its solubility is …
Viscous medium promotes cooperation in the pathogenic bacterium Pseudomonas aeruginosa
There has been extensive theoretical debate over whether population viscosity (limited
dispersal) can favour cooperation. While limited dispersal increases the probability of …
dispersal) can favour cooperation. While limited dispersal increases the probability of …
Phenotypic plasticity of a cooperative behaviour in bacteria
R Kümmerli, N Jiricny, LS Clarke… - Journal of …, 2009 - academic.oup.com
There is strong evidence that natural selection can favour phenotypic plasticity as a
mechanism to maximize fitness in animals. Here, we aim to investigate phenotypic plasticity …
mechanism to maximize fitness in animals. Here, we aim to investigate phenotypic plasticity …
Limited dispersal, budding dispersal, and cooperation: an experimental study
Numerous theoretical studies have investigated how limited dispersal may provide an
explanation for the evolution of cooperation, by leading to interactions between relatives …
explanation for the evolution of cooperation, by leading to interactions between relatives …
Density dependence and cooperation: theory and a test with bacteria
Although cooperative systems can persist in nature despite the potential for exploitation by
noncooperators, it is often observed that small changes in population demography can tip …
noncooperators, it is often observed that small changes in population demography can tip …
Role of iron in plant–microbe interactions
Iron is an essential micronutrient for plants and associated microorganisms. Iron nutrition of
these organisms relies on the soil supply. However, bioavailability of iron in cultivated soils …
these organisms relies on the soil supply. However, bioavailability of iron in cultivated soils …