The chemokine CCL20 and its receptor CCR6 in human malignancy with focus on colorectal cancer
P Ghadjar, C Rubie, DM Aebersold… - International journal of …, 2009 - Wiley Online Library
Chemokines are a superfamily of small chemotactic cytokines, which interact with their G‐
protein‐coupled receptors. These interactions regulate multiple physiological functions …
protein‐coupled receptors. These interactions regulate multiple physiological functions …
CC chemokine receptor 6–regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE
A Reboldi, C Coisne, D Baumjohann, F Benvenuto… - Nature …, 2009 - nature.com
Interleukin 17–producing T helper cells (T H-17 cells) are important in experimental
autoimmune encephalomyelitis, but their route of entry into the central nervous system …
autoimmune encephalomyelitis, but their route of entry into the central nervous system …
Genetics of inflammatory bowel disease: implications for disease pathogenesis and natural history
CW Lees, J Satsangi - Expert review of gastroenterology & …, 2009 - Taylor & Francis
Epidemiological data, detailed molecular studies and recent genome-wide association
studies strongly suggest that ulcerative colitis (UC) and Crohn's disease (CD) are related …
studies strongly suggest that ulcerative colitis (UC) and Crohn's disease (CD) are related …
[图书][B] Wintrobe's clinical hematology
MM Wintrobe - 2009 - books.google.com
Now available in a thoroughly revised Twelfth Edition, Wintrobe's Clinical Hematology
continues to be an industry leader with its ability to correlate basic science with the clinical …
continues to be an industry leader with its ability to correlate basic science with the clinical …
[HTML][HTML] The roles of CCR6 in migration of Th17 cells and regulation of effector T-cell balance in the gut
Migration and trafficking receptors of Th17 cells to mucosal tissues have been unclear. We
report that Th17 cells preferentially migrate to the intestine and associated lymphoid tissues …
report that Th17 cells preferentially migrate to the intestine and associated lymphoid tissues …
CCR6 is required for IL-23–induced psoriasis-like inflammation in mice
MN Hedrick, AS Lonsdorf… - The Journal of …, 2009 - Am Soc Clin Investig
Psoriasis is a common immune-mediated chronic inflammatory skin disorder, but the
mechanisms of pathogenesis are still poorly understood. IL-23 is expressed in psoriatic skin …
mechanisms of pathogenesis are still poorly understood. IL-23 is expressed in psoriatic skin …
Inhibition of CCR6 function reduces the severity of experimental autoimmune encephalomyelitis via effects on the priming phase of the immune response
A Liston, RE Kohler, S Townley… - The Journal of …, 2009 - journals.aai.org
Chemokines are essential for homeostasis and activation of the immune system. The
chemokine ligand/receptor pairing CCL20/CCR6 is interesting because these molecules …
chemokine ligand/receptor pairing CCL20/CCR6 is interesting because these molecules …
Contribution of Flagellin Pattern Recognition to Intestinal Inflammation during Salmonella enterica Serotype Typhimurium Infection
Salmonella enterica serotype Typhimurium causes acute inflammatory diarrhea in humans.
Flagella contribute to intestinal inflammation, but the mechanism remains unclear since most …
Flagella contribute to intestinal inflammation, but the mechanism remains unclear since most …
[HTML][HTML] Human Th17 cells in infection and autoimmunity
F Sallusto, A Lanzavecchia - Microbes and Infection, 2009 - Elsevier
IL-17-producing T cells (Th17) have been identified in mice as a distinct lineage of CD4+ T
helper cells. Since their discovery, efforts have been made in characterizing human Th17 …
helper cells. Since their discovery, efforts have been made in characterizing human Th17 …
Macrophage inflammatory protein-3alpha plays a key role in the inflammatory cascade in rat focal cerebral ischemia
Y Terao, H Ohta, A Oda, Y Nakagaito, Y Kiyota… - Neuroscience …, 2009 - Elsevier
Although hypothermia is one of the most robust neuroprotectants clinically available, its
underlying mechanisms remain unclear. Through microarray gene expression analysis, we …
underlying mechanisms remain unclear. Through microarray gene expression analysis, we …