Abstract Background Most European countries are ethnically and culturally diverse.
Globally, cardiovascular disease (CVD) is the leading cause of death. The major risk factors …

This article discusses specific dietary factors as well as dietary patterns that affect the major
coronary heart disease (CHD) lipid risk factors (ie, LDL-C, HDL-C, and TG). Based on a very …

Background—Trait optimism (positive future expectations) and cynical, hostile attitudes
toward others have not been studied together in relation to incident coronary heart disease …

Background Overexpression of the fatty acid synthase (FASN) gene has been implicated in
prostate carcinogenesis. We sought to directly assess the oncogenic potential of FASN …

Background Although physically active individuals have a lower risk of developing colorectal
cancer, few studies have examined whether exercise benefits colorectal cancer survivors …

Background: Genome-wide association studies have identified novel type 2 diabetes loci,
each of which has a modest impact on risk. Objective: To examine the joint effects of several …

Background A widely held hypothesis is that interactions between genetic predisposition
and Western-type lifestyle contribute to the epidemic of type 2 diabetes (T2D). No study has …

Background Evidence from observational studies suggests that inadequate folate status
enhances colorectal carcinogenesis, but results from some randomized trials do not support …

Alcohol consumers show strong variations in demographic characteristics, alcohol intake,
frequency, duration and profile of consumption. Individuals consuming up to two drinks per …

The cardioprotective effects of moderate alcohol consumption have been well documented
in animal models and in humans. Protection afforded against ischemia and reperfusion …