The AQP structure and functional implications
T Wspalz, Y Fujiyoshi, A Engel - Aquaporins, 2009 - Springer
Progress in the structure determination of AQPs has led to a deep understanding of water
and solute permeation by these small integral membrane proteins. The atomic structures …
and solute permeation by these small integral membrane proteins. The atomic structures …
Structural function of MIP/aquaporin 0 in the eye lens; genetic defects lead to congenital inherited cataracts
AB Chepelinsky - Aquaporins, 2009 - Springer
Aquaporin 0 (AQP0) was originally characterized as a membrane intrinsic protein,
specifically expressed in the lens fibers of the ocular lens and designated MIP, for major …
specifically expressed in the lens fibers of the ocular lens and designated MIP, for major …
MALDI imaging mass spectrometry of integral membrane proteins from ocular lens and retinal tissue
A tissue preparation protocol for MALDI (matrix-assisted laser desorption/ionization) imaging
mass spectrometry of integral membrane proteins was developed using ocular lens and …
mass spectrometry of integral membrane proteins was developed using ocular lens and …
Intact AQP0 performs cell-to-cell adhesion
SS Kumari, K Varadaraj - Biochemical and biophysical research …, 2009 - Elsevier
Aquaporins (AQPs) constitute a major conduit for movement of water across plasma
membranes. AQP0 is expressed in the fiber cells and is critical for lens transparency and …
membranes. AQP0 is expressed in the fiber cells and is critical for lens transparency and …
Aquaporin-1-facilitated keratocyte migration in cell culture and in vivo corneal wound healing models
J Ruiz-Ederra, AS Verkman - Experimental eye research, 2009 - Elsevier
Aquaporin-1 (AQP1) water channels are expressed in corneal keratocytes, which become
activated and migrate following corneal wounding. The purpose of this study was to …
activated and migrate following corneal wounding. The purpose of this study was to …
The effects of GPX-1 knockout on membrane transport and intracellular homeostasis in the lens
H Wang, J Gao, X Sun, FJ Martinez-Wittinghan… - Journal of Membrane …, 2009 - Springer
Abstract Glutathione peroxidase-1 (GPX-1) is an enzyme that protects the lens against H 2 O
2-mediated oxidative damage. The purpose of the present study was to determine the effects …
2-mediated oxidative damage. The purpose of the present study was to determine the effects …
Differentiation-dependent modification and subcellular distribution of aquaporin-0 suggests multiple functional roles in the rat lens
AC Grey, L Li, MD Jacobs, KL Schey, PJ Donaldson - Differentiation, 2009 - Elsevier
Using immunohistochemistry and mass spectrometry, differentiation-dependent changes in
the subcellular distribution and processing of aquaporin-0 (AQP0) have been mapped in the …
the subcellular distribution and processing of aquaporin-0 (AQP0) have been mapped in the …
Sorting of lens aquaporins and connexins into raft and nonraft bilayers: role of protein homo-oligomerization
J Tong, MM Briggs, D Mlaver, A Vidal, TJ McIntosh - Biophysical journal, 2009 - cell.com
Two classes of channel-forming proteins in the eye lens, the water channel aquaporin-0
(AQP-0) and the connexins Cx46 and Cx50, are preferentially located in different regions of …
(AQP-0) and the connexins Cx46 and Cx50, are preferentially located in different regions of …