TORC2 plasma membrane localization is essential for cell viability and restricted to a distinct domain

D Berchtold, TC Walther - Molecular biology of the cell, 2009 - Am Soc Cell Biol
The conserved target of rapamycin (TOR) kinases regulate many aspects of cellular
physiology. They exist in two distinct complexes, termed TOR complex 1 (TORC1) and TOR …

Reconstruction of signaling networks regulating fungal morphogenesis by transcriptomics

V Meyer, M Arentshorst, SJ Flitter, BM Nitsche… - Eukaryotic …, 2009 - Am Soc Microbiol
Coordinated control of hyphal elongation and branching is essential for sustaining mycelial
growth of filamentous fungi. In order to study the molecular machinery ensuring polarity …

Synthetic Genetic Interactions: Allele Dependence, Uses, and Conservation

JV Gray, SA Krause - Advances in Genetics, 2009 - Elsevier
Genetic interactions occur between a pair of genes when the phenotype of the double
mutant leads to an unexpected phenotype, one that is not predicted from the phenotypes of …

Lipids as Trans Acting Factors for the Transport of Integral Membrane Proteins

M Fischer - 2009 - archiv.ub.uni-heidelberg.de
Ist2 is an integral, polytopic membrane protein of Saccharomyces cerevisiae. Some of the
IST2 mRNA is localized to the bud tip of the daughter cell, where the protein is locally …

Functions of Phosphatidylinositol 4-Phosphate 5 Kinases in Actin Cytoskeletal Regulation During Phagocytosis

YS Mao - 2009 - utswmed-ir.tdl.org
Abstract Phosphatidylinositol (4, 5)-bisphosphate (PIP2) is a crucial signaling
phosphoinositide at the plasma membrane (PM) which mediates a variety of biochemical …

[PDF][PDF] Charakterisierung der TOR-Komplexe in Schizosaccharomyces pombe

G von Coelln - 2009 - osnadocs.ub.uni-osnabrueck.de
Cells need to sense their living conditions and react to it. The TOR (" Target of Rapamycin")-
signaling pathway plays an important role in controlling cell growth in response to nutrients …