Regulation of central angiotensin type 1 receptors and sympathetic outflow in heart failure

IH Zucker, HD Schultz, KP Patel… - American Journal of …, 2009 - journals.physiology.org
Angiotensin type 1 receptors (AT1Rs) play a critical role in a variety of physiological
functions and pathophysiological states. They have been strongly implicated in the …

Role of HIF-1α in the regulation ACE and ACE2 expression in hypoxic human pulmonary artery smooth muscle cells

R Zhang, Y Wu, M Zhao, C Liu, L Zhou… - … of Physiology-Lung …, 2009 - journals.physiology.org
Angiotensin-converting enzyme (ACE) enhances the proliferation and migration of
pulmonary artery smooth muscle cells (PASMCs), which contribute to the pathogenesis of …

Evidence for angiotensin-converting enzyme 2 as a therapeutic target for the prevention of pulmonary hypertension

AJ Ferreira, V Shenoy, Y Yamazato… - American journal of …, 2009 - atsjournals.org
Rationale: It has been proposed that an activated renin angiotensin system (RAS) causes an
imbalance between the vasoconstrictive and vasodilator mechanisms involving the …

Localization of ACE2 in the renal vasculature: amplification by angiotensin II type 1 receptor blockade using telmisartan

MJ Soler, M Ye, J Wysocki, J William… - American Journal …, 2009 - journals.physiology.org
Angiotensin-converting enzyme (ACE) 2 is a carboxypeptidase that degrades angiotensin II
and other peptides. In the kidney, ACE2 localization within the glomerulus and tubules is cell …

Prevention of pulmonary hypertension by angiotensin-converting enzyme 2 gene transfer

Y Yamazato, AJ Ferreira, KH Hong, S Sriramula… - …, 2009 - Am Heart Assoc
In spite of recent advancements in the treatment of pulmonary hypertension, successful
control has yet to be accomplished. The abundant presence of angiotensin-converting …

Characterization of a local renin‐angiotensin system in rat gingival tissue

CF Santos, AE Akashi, TJ Dionísio… - Journal of …, 2009 - Wiley Online Library
Background: The systemic renin‐angiotensin system (RAS) promotes the plasmatic
production of angiotensin (Ang) II, which acts through interaction with specific receptors …

Decreased expression of angiotensin-converting enzyme 2 in pancreatic ductal adenocarcinoma is associated with tumor progression

L Zhou, R Zhang, W Yao, J Wang, A Qian… - The Tohoku journal of …, 2009 - jstage.jst.go.jp
Angiotensin II (ANG II), the biologically active peptide of the renin-angiotensin system (RAS),
is generated by angiotensin-converting enzyme (ACE) and is a regulator of cardiovascular …

Actions of selected cardiovascular hormones on arterial stiffness and wave reflections

WW Nichols, BJ Epstein - Current pharmaceutical design, 2009 - ingentaconnect.com
The large conduit arteries of the thorax and abdomen are elastic while those in the arms and
legs are muscular. Alterations in wall properties of elastic arteries occur over time and are …

Sistema Renina Angiotensina Renal: El papel de la Angiotensina 1-7 y la Enzima Convertidora de Angiotensina 2 en el riñón.

J Villalobos, L Figueira, VL Colina - Vitae, 2009 - saber.ucv.ve
El sistema renina angiotensina (SRA) juega un papel muy importante en diversos procesos
fisiopatológicos, siendo la Angiotensina II (Ang II) uno de los principales mediadores …

自发性高血压大鼠肾脏血管紧张素转换酶2 的表达

吴逸南, 葛志明, 李方, 贺红, 姜虹… - 山东大学学报(医学 …, 2009 - yxbwk.njournal.sdu.edu.cn
目的观察不同月龄的自发性高血压大鼠(SHR) 的肾脏血管紧张素转换酶2 (ACE2) 的mRNA
和蛋白质表达水平, 探讨ACE2 与血压状态的内在联系. 方法12 周龄雄性自发性高血压大鼠 …