Hydrogels in regenerative medicine
Hydrogels, due to their unique biocompatibility, flexible methods of synthesis, range of
constituents, and desirable physical characteristics, have been the material of choice for …
constituents, and desirable physical characteristics, have been the material of choice for …
Growth factors, matrices, and forces combine and control stem cells
Stem cell fate is influenced by a number of factors and interactions that require robust control
for safe and effective regeneration of functional tissue. Coordinated interactions with soluble …
for safe and effective regeneration of functional tissue. Coordinated interactions with soluble …
Engineered microenvironments for controlled stem cell differentiation
JA Burdick, G Vunjak-Novakovic - Tissue Engineering Part A, 2009 - liebertpub.com
In a developing organism, tissues emerge from coordinated sequences of cell renewal,
differentiation, and assembly that are orchestrated by spatial and temporal gradients of …
differentiation, and assembly that are orchestrated by spatial and temporal gradients of …
Influence of three-dimensional hyaluronic acid microenvironments on mesenchymal stem cell chondrogenesis
C Chung, JA Burdick - Tissue Engineering Part A, 2009 - liebertpub.com
Mesenchymal stem cells (MSCs) are multipotent progenitor cells whose plasticity and self-
renewal capacity have generated significant interest for applications in tissue engineering …
renewal capacity have generated significant interest for applications in tissue engineering …
Self-assembled hyaluronic acid nanoparticles as a potential drug carrier for cancer therapy: synthesis, characterization, and in vivo biodistribution
To develop a nano-sized drug delivery system for cancer therapy, amphiphilic hyaluronic
acid conjugates were synthesized by chemical conjugation of hydrophobic 5β-cholanic acid …
acid conjugates were synthesized by chemical conjugation of hydrophobic 5β-cholanic acid …
Engineering the embryoid body microenvironment to direct embryonic stem cell differentiation
AM Bratt‐Leal, RL Carpenedo… - Biotechnology …, 2009 - Wiley Online Library
Embryonic stem cells (ESCs) are pluripotent cells capable of differentiating into all somatic
and germ cell types. The intrinsic ability of pluripotent cells to generate a vast array of …
and germ cell types. The intrinsic ability of pluripotent cells to generate a vast array of …
Validation of the cardiosphere method to culture cardiac progenitor cells from myocardial tissue
Background At least four laboratories have shown that endogenous cardiac progenitor cells
(CPCs) can be grown directly from adult heart tissue in primary culture, as cardiospheres or …
(CPCs) can be grown directly from adult heart tissue in primary culture, as cardiospheres or …
Layer‐by‐layer films as a biomimetic reservoir for rhBMP‐2 delivery: controlled differentiation of myoblasts to osteoblasts
T Crouzier, K Ren, C Nicolas, C Roy, C Picart - Small, 2009 - Wiley Online Library
Efficient delivery of growth or survival factors to cells is one of the most important long‐term
challenges of current cell‐based tissue engineering strategies. The extracellular matrix acts …
challenges of current cell‐based tissue engineering strategies. The extracellular matrix acts …
Generation of human embryonic stem cell‐derived mesoderm and cardiac cells using size‐specified aggregates in an oxygen‐controlled bioreactor
S Niebruegge, CL Bauwens, R Peerani… - Biotechnology and …, 2009 - Wiley Online Library
The ability to generate human pluripotent stem cell‐derived cell types at sufficiently high
numbers and in a reproducible manner is fundamental for clinical and biopharmaceutical …
numbers and in a reproducible manner is fundamental for clinical and biopharmaceutical …
Mechanically robust and bioadhesive collagen and photocrosslinkable hyaluronic acid semi-interpenetrating networks
In this work, we present a class of hydrogels that leverage the favorable properties of the
photo-cross-linkable hyaluronic acid (HA) and semi-interpenetrating collagen components …
photo-cross-linkable hyaluronic acid (HA) and semi-interpenetrating collagen components …