Tissue remodelling through branching morphogenesis

M Affolter, R Zeller, E Caussinus - Nature reviews Molecular cell biology, 2009 - nature.com
Branched structures are evident at all levels of organization in living organisms. Many
organs, such as the vascular system, lung, kidney and mammary gland, are heavily …

Developmental phenotype of a membrane only estrogen receptor α (MOER) mouse

A Pedram, M Razandi, JK Kim, F O'Mahony… - Journal of Biological …, 2009 - ASBMB
Estrogen receptors (ERs) α and β exist as nuclear, cytoplasmic, and membrane cellular
pools in a wide variety of organs. The relative contributions of each ERα pool to in vivo …

Estrogen rapidly activates the PI3K/AKT pathway and hypoxia-inducible factor 1 and induces vascular endothelial growth factor A expression in luminal epithelial cells …

AA Kazi, KH Molitoris, RD Koos - Biology of reproduction, 2009 - academic.oup.com
We have previously shown that 17beta-estradiol (E2) increases vascular endothelial growth
factor A (Vegfa) gene expression in the rat uterus, resulting in increased microvascular …

Defects of prostate development and reproductive system in the estrogen receptor-α null male mice

M Chen, I Hsu, A Wolfe, S Radovick, KH Huang… - …, 2009 - academic.oup.com
The estrogen receptor-α knockout (ERαKO, ERα−/−) mice were generated via the Cre-loxP
system by mating floxed ERα mice with β-actin (ACTB)-Cre mice. The impact of ERα gene …

Generation and characterization of a complete null estrogen receptor α mouse using Cre/LoxP technology

M Chen, A Wolfe, X Wang, C Chang, S Yeh… - Molecular and cellular …, 2009 - Springer
Conventional estrogen receptor α knockout (neo-ERαKO, neo-ERα−/−) mice contain a
truncated and chimeric ERα fusion protein that retains 35% estrogen-dependent …

Keratin 18 attenuates estrogen receptor α-mediated signaling by sequestering LRP16 in cytoplasm

Y Meng, Z Wu, X Yin, Y Zhao, M Chen, Y Si, J Yang… - BMC Cell Biology, 2009 - Springer
Background Oncogenesis in breast cancer is often associated with excess estrogen receptor
α (ERα) activation and overexpression of its coactivators. LRP16 is both an ERα target gene …

[HTML][HTML] The Ron receptor tyrosine kinase negatively regulates mammary gland branching morphogenesis

SE Meyer, GM Zinser, WD Stuart, P Pathrose… - Developmental …, 2009 - Elsevier
The Ron receptor tyrosine kinase is expressed in normal breast tissue and is overexpressed
in approximately 50% of human breast cancers. Despite the recent studies on Ron in breast …

The regulation of MS-KIF18A expression and cross talk with estrogen receptor

M Zusev, D Benayahu - PloS one, 2009 - journals.plos.org
This study provides a novel view on the interactions between the MS-KIF18A, a kinesin
protein, and estrogen receptor alpha (ERα) which were studied in vivo and in vitro …

雌激素受体α 和β 在人正常乳腺组织中的表达及意义

李嗣杰, 韩冰, 范志民, 付彤, 宋东… - 吉林大学学报(医学版 …, 2009 - xuebao.jlu.edu.cn
目的: 观察雌激素受体α (ERα) 和β (ERβ) 在人正常乳腺组织细胞中的定位, 为探讨ERα 和ERβ
与乳腺组织生长发育的关系奠定基础. 方法: 应用免疫组织化学的方法, 检测16 …

The Ron Receptor Tyrosine Kinase in Tissue Morphogenesis

S Meyer - 2009 - rave.ohiolink.edu
The Ron receptor tyrosine kinase is overexpressed in many human cancers including
colorectal and breast, and studies have established Ron as a predictor of disease outcome …