Tripartite synapses: astrocytes process and control synaptic information

G Perea, M Navarrete, A Araque - Trends in neurosciences, 2009 - cell.com
The term 'tripartite synapse'refers to a concept in synaptic physiology based on the
demonstration of the existence of bidirectional communication between astrocytes and …

Astrocytes and the regulation of cerebral blood flow

RC Koehler, RJ Roman, DR Harder - Trends in neurosciences, 2009 - cell.com
Moment-to-moment changes in local neuronal activity lead to dynamic changes in cerebral
blood flow. Emerging evidence implicates astrocytes as one of the key players in …

Astrocytic modulation of sleep homeostasis and cognitive consequences of sleep loss

MM Halassa, C Florian, T Fellin, JR Munoz, SY Lee… - Neuron, 2009 - cell.com
Astrocytes modulate neuronal activity by releasing chemical transmitters via a process
termed gliotransmission. The role of this process in the control of behavior is unknown …

Synchronous hyperactivity and intercellular calcium waves in astrocytes in Alzheimer mice

KV Kuchibhotla, CR Lattarulo, BT Hyman, BJ Bacskai - Science, 2009 - science.org
Although senile plaques focally disrupt neuronal health, the functional response of
astrocytes to Alzheimer's disease pathology is unknown. Using multiphoton fluorescence …

Direct activation of sparse, distributed populations of cortical neurons by electrical microstimulation

MH Histed, V Bonin, RC Reid - Neuron, 2009 - cell.com
For over a century, electrical microstimulation has been the most direct method for causally
linking brain function with behavior. Despite this long history, it is still unclear how the activity …

Modeling the hemodynamic response function in fMRI: efficiency, bias and mis-modeling

MA Lindquist, JM Loh, LY Atlas, TD Wager - Neuroimage, 2009 - Elsevier
Most brain research to date have focused on studying the amplitude of evoked fMRI
responses, though there has recently been an increased interest in measuring onset, peak …

Motor behavior activates Bergmann glial networks

A Nimmerjahn, EA Mukamel, MJ Schnitzer - Neuron, 2009 - cell.com
Although it is firmly established that neuronal activity is a prime determinant of animal
behavior, relationships between astrocytic excitation and animal behavior have remained …

What's new in neuroimaging methods?

PA Bandettini - Annals of the New York Academy of Sciences, 2009 - Wiley Online Library
The rapid advancement of neuroimaging methodology and its growing availability has
transformed neuroscience research. The answers to many questions that we ask about how …

Visually evoked activity in cortical cells imaged in freely moving animals

J Sawinski, DJ Wallace… - Proceedings of the …, 2009 - National Acad Sciences
We describe a miniaturized head-mounted multiphoton microscope and its use for recording
Ca2+ transients from the somata of layer 2/3 neurons in the visual cortex of awake, freely …

Tripartite synapses: roles for astrocytic purines in the control of synaptic physiology and behavior

MM Halassa, T Fellin, PG Haydon - Neuropharmacology, 2009 - Elsevier
Astrocytes are known to release several transmitters to impact neuronal activity. Cell-specific
molecular genetic attenuation of vesicular release has shown that ATP is a primary …