MicroRNAs: control and loss of control in human physiology and disease
M Li, C Marin-Muller, U Bharadwaj, KH Chow… - World journal of …, 2009 - Springer
Abstract Analysis of the human genome indicates that a large fraction of the genome
sequences are RNAs that do not encode any proteins, also known as non-coding RNAs …
sequences are RNAs that do not encode any proteins, also known as non-coding RNAs …
MicroRNA profiling identifies miR-34a and miR-21 and their target genes JAG1 and WNT1 in the coordinate regulation of dendritic cell differentiation
ST Hashimi, JA Fulcher, MH Chang… - Blood, The Journal …, 2009 - ashpublications.org
MicroRNAs (miRNAs, miRs) modulate a multitude of cellular events. Here, we identify
functional miRNA-protein networks that regulate human monocyte-derived dendritic cell …
functional miRNA-protein networks that regulate human monocyte-derived dendritic cell …
Alternative processing of primary microRNA transcripts by Drosha generates 5′ end variation of mature microRNA
Background It is generally believed that the miRNA processing machinery ensures the
generation of a mature miRNA with a fixed sequence, particularly at its 5′ end. However …
generation of a mature miRNA with a fixed sequence, particularly at its 5′ end. However …
A high throughput experimental approach to identify miRNA targets in human cells
The study of human microRNAs is seriously hampered by the lack of proper tools allowing
genome-wide identification of miRNA targets. We performed Ribonucleoprotein …
genome-wide identification of miRNA targets. We performed Ribonucleoprotein …
The microRNA-30 family is required for vertebrate hepatobiliary development
NJ Hand, ZR Master, SF Eauclaire, DE Weinblatt… - Gastroenterology, 2009 - Elsevier
BACKGROUND & AIMS: The function of microRNA (miRNA) in liver development is
unknown. To address this issue, we characterized miRNA expression in the embryonic …
unknown. To address this issue, we characterized miRNA expression in the embryonic …
MicroRNA expression profiling in Imatinib-resistant Chronic Myeloid Leukemia patients without clinically significant ABL1-mutations
E San José-Enériz, J Román-Gómez… - Molecular Cancer, 2009 - Springer
Abstract The development of Imatinib Mesylate (IM), the first specific inhibitor of BCR-ABL1,
has had a major impact in patients with Chronic Myeloid Leukemia (CML), establishing IM …
has had a major impact in patients with Chronic Myeloid Leukemia (CML), establishing IM …
[HTML][HTML] miRNA profiling of B-cell subsets: specific miRNA profile for germinal center B cells with variation between centroblasts and centrocytes
MicroRNAs (miRNAs) are an important class of small RNAs that regulate gene expression at
the post-transcriptional level. It has become evident that miRNAs are involved in …
the post-transcriptional level. It has become evident that miRNAs are involved in …
Hematopoiesis-related microRNA expression in myelodysplastic syndromes
MicroRNAs (miRNAs) are negative regulators of expression of genes involved in
hematopoiesis. The present study sought to link hematopoiesis-relevant miRNAs with …
hematopoiesis. The present study sought to link hematopoiesis-relevant miRNAs with …
MicroRNA‐223 reversibly regulates erythroid and megakaryocytic differentiation of K562 cells
JY Yuan, F Wang, J Yu, GH Yang… - Journal of cellular …, 2009 - Wiley Online Library
MicroRNAs (miRNAs) are thought to modulate a variety of cellular events. Several studies
have revealed the functions of miR‐223 in granulopoiesis. Here we analysed miR‐223 …
have revealed the functions of miR‐223 in granulopoiesis. Here we analysed miR‐223 …
Micro-RNAs and their potential target genes in leukemia pathogenesis
C Dong, M Ji, C Ji - Cancer biology & therapy, 2009 - Taylor & Francis
Leukemia is the most common hematological malignancy, characterized by distorted
proliferation and development of leukocytes and their precursors in the blood and bone …
proliferation and development of leukocytes and their precursors in the blood and bone …