Orexin/hypocretin: a neuropeptide at the interface of sleep, energy homeostasis, and reward system
N Tsujino, T Sakurai - Pharmacological reviews, 2009 - ASPET
Recent studies have implicated the orexin system as a critical regulator of sleep/wake states
as well as feeding behavior and reward processes. Orexin deficiency results in narcolepsy …
as well as feeding behavior and reward processes. Orexin deficiency results in narcolepsy …
Biomedical application of orexin/hypocretin receptor ligands in neuroscience
C Boss, C Brisbare-Roch, F Jenck - Journal of medicinal chemistry, 2009 - ACS Publications
Orexin/hypocretin neuropeptides (orexin-A or hypocretin1 and orexin-B or hypocretin2) are
peptides discovered and published in 1998 by two independent research groups as the …
peptides discovered and published in 1998 by two independent research groups as the …
The role of thermogenesis in antipsychotic drug‐induced weight gain
A Stefanidis, ANA Verty, AM Allen, NC Owens… - …, 2009 - Wiley Online Library
The administration of antipsychotic drugs to human patients or experimental animals leads
to significant weight gain, which is widely presumed to be driven by hyperphagia; however …
to significant weight gain, which is widely presumed to be driven by hyperphagia; however …
Hypocretin/Orexin neuropeptides: participation in the control of sleep-wakefulness cycle and energy homeostasis
A Nunez, ML Rodrigo-Angulo… - Current …, 2009 - ingentaconnect.com
Hypocretins or orexins (Hcrt/Orx) are hypothalamic neuropeptides that are synthesized by
neurons located mainly in the perifornical area of the posterolateral hypothalamus. These …
neurons located mainly in the perifornical area of the posterolateral hypothalamus. These …
Integrative physiology of orexins and orexin receptors
Recent studies have established that the orexin system is a critical regulator of sleep/wake
states. Deficiency of orexin signaling results in the sleep disorder narcolepsy-cataplexy in …
states. Deficiency of orexin signaling results in the sleep disorder narcolepsy-cataplexy in …
Role of the ventromedial hypothalamic orexin‐1 receptors in regulation of gastric acid secretion in conscious rats
Orexins play an important role on the central nervous system to modulate gastric acid
secretion. The orexin receptors are distributed within the hypothalamus, and expression of …
secretion. The orexin receptors are distributed within the hypothalamus, and expression of …
[PDF][PDF] Yeni keşif nöropeptitlerden: Oreksin
MG Karadağ, M Aksoy - Gözde Tıp Dergisi, 2009 - jag.journalagent.com
Orexin A and orexin B are two peptides derived by proteolytic cleavage from a 130 amino
acid precursor prepro-orexin. Prepro orexin is found in the hypothalamus and, to a markedly …
acid precursor prepro-orexin. Prepro orexin is found in the hypothalamus and, to a markedly …