Hepatitis B virus resistance to nucleos (t) ide analogues
F Zoulim, S Locarnini - Gastroenterology, 2009 - Elsevier
Patients with chronic hepatitis B (CHB) can be successfully treated using nucleos (t) ide
analogs (NA), but drug-resistant hepatitis B virus (HBV) mutants frequently arise, leading to …
analogs (NA), but drug-resistant hepatitis B virus (HBV) mutants frequently arise, leading to …
[PDF][PDF] Antiviral resistance and hepatitis B therapy
MG Ghany, EC Doo - Hepatology, 2009 - Wiley Online Library
The management of chronic hepatitis B currently rests with long‐term therapy using oral
nucleoside analogs. The major limitation of long‐term therapy is antiviral resistance …
nucleoside analogs. The major limitation of long‐term therapy is antiviral resistance …
Chronic hepatitis B: update 2009
ASF Lok, BJ McMahon - Hepatology, 2009 - journals.lww.com
The 2009 update of the American Association for the Study of Liver Diseases (AASLD)
Practice Guidelines for Management of Chronic Hepatitis B are now posted online at www …
Practice Guidelines for Management of Chronic Hepatitis B are now posted online at www …
Sustained response of hepatitis B e antigen-negative patients 3 years after treatment with peginterferon alfa-2a
P Marcellin, F Bonino, GKK Lau, P Farci, C Yurdaydin… - Gastroenterology, 2009 - Elsevier
BACKGROUND & AIMS: Patients with hepatitis B e antigen (HBeAg)–negative chronic
hepatitis B treated with peginterferon alfa-2a with or without lamivudine achieve significantly …
hepatitis B treated with peginterferon alfa-2a with or without lamivudine achieve significantly …
The history of antiretrovirals: key discoveries over the past 25 years
E De Clercq - Reviews in medical virology, 2009 - Wiley Online Library
Abstract Within 25 years after zidovudine (3′‐azido‐2′, 3′‐dideoxythymidine, AZT) was
first described as an inhibitor of HIV replication, 25 anti‐HIV drugs have been formally …
first described as an inhibitor of HIV replication, 25 anti‐HIV drugs have been formally …
Hepatitis B virus variants
W Chotiyaputta, ASF Lok - Nature reviews Gastroenterology & …, 2009 - nature.com
HBV replicates through reverse transcription of an RNA intermediate; the inherent lack of
proofreading causes a high mutation frequency. Mutations in the precore and core promoter …
proofreading causes a high mutation frequency. Mutations in the precore and core promoter …
Hepatitis B and hepatitis C in 2009
P Marcellin - Liver International, 2009 - Wiley Online Library
Hepatitis B virus (HBV) and hepatitis C virus (HCV) infections are among the most frequent
viral infections in humans, and represent a major global public health problem. HBV‐and …
viral infections in humans, and represent a major global public health problem. HBV‐and …
HBeAg seroconversion as an important end point in the treatment of chronic hepatitis B
YF Liaw - Hepatology international, 2009 - Springer
During the natural history of chronic hepatitis B virus (HBV) infection, the loss of serum
hepatitis B e antigen (HBeAg) and the development of anti-HBe antibodies (HBeAg …
hepatitis B e antigen (HBeAg) and the development of anti-HBe antibodies (HBeAg …
Trends in waiting list registration for liver transplantation for viral hepatitis in the United States
WR Kim, NA Terrault, RA Pedersen, TM Therneau… - Gastroenterology, 2009 - Elsevier
BACKGROUND & AIMS: In the last decade, significant progress has been made in the
treatment of liver disease associated with chronic hepatitis, especially in patients infected …
treatment of liver disease associated with chronic hepatitis, especially in patients infected …
[HTML][HTML] Antiviral therapy of chronic hepatitis B: opportunities and challenges in Asia
YF Liaw - Journal of Hepatology, 2009 - Elsevier
Asia comprises more than 40 countries encompassing a wide geographic area with a very
large population. Many of these countries have low-income economies together with high …
large population. Many of these countries have low-income economies together with high …