Endothelial progenitor cells: identity defined?

F Timmermans, J Plum, MC Yöder… - Journal of cellular …, 2009 - Wiley Online Library
• Introduction• The proof‐of‐concept in vivo: the cell, the read‐out and the animal model‐The
CEPC: Still a putative cell‐Do CEPCs play an essential role in vascular (patho) physiology …

Therapies for hyperglycaemia-induced diabetic complications: from animal models to clinical trials

NA Calcutt, ME Cooper, TS Kern… - Nature Reviews Drug …, 2009 - nature.com
Long-term diabetes increases the likelihood of developing secondary damage to numerous
systems, and these complications represent a substantial cause of morbidity and mortality …

Mobilization of Bone Marrow-Derived Oct-4+ SSEA-4+ Very Small Embryonic-Like Stem Cells in Patients With Acute Myocardial Infarction

W Wojakowski, M Tendera, M Kucia… - Journal of the American …, 2009 - jacc.org
Objectives: This study sought to assess of the mobilization of nonhematopoietic very small
embryonic-like stem cells (VSELs) in acute myocardial infarction (MI). Background: Acute MI …

Promoting mechanisms of vascular health: circulating progenitor cells, angiogenesis, and reverse cholesterol transport

PR Moreno, J Sanz, V Fuster - Journal of the American College of …, 2009 - jacc.org
To understand and promote vascular health, we must reduce the aggression to the vessel
wall and enhance the physiologic mechanisms leading to restoration of vessel wall function …

Low CD34+ cell count and metabolic syndrome synergistically increase the risk of adverse outcomes

GP Fadini, S de Kreutzenberg, C Agostini, E Boscaro… - Atherosclerosis, 2009 - Elsevier
OBJECTIVES: Metabolic syndrome (MetS) associates with endothelial dysfunction and a
high risk of cardiovascular events and death. Circulating progenitor cells have been shown …

[HTML][HTML] Recovery from hind limb ischemia is less effective in type 2 than in type 1 diabetic mice: roles of endothelial nitric oxide synthase and endothelial progenitor …

J Yan, G Tie, B Park, Y Yan, PT Nowicki… - Journal of vascular …, 2009 - Elsevier
OBJECTIVE: We sought to directly compare the effects of type 1 and type 2 diabetes on
postischemic neovascularization and evaluate the mechanisms underlying differences …

Stem cell therapy with overexpressed VEGF and PDGF genes improves cardiac function in a rat infarct model

H Das, JC George, M Joseph, M Das, N Abdulhameed… - PloS one, 2009 - journals.plos.org
Background Therapeutic potential was evaluated in a rat model of myocardial infarction
using nanofiber-expanded human cord blood derived hematopoietic stem cells …

The 9p21 myocardial infarction risk allele increases risk of peripheral artery disease in older people

C Cluett, MMG McDermott, J Guralnik… - Circulation …, 2009 - Am Heart Assoc
Background—A common variant at chromosome 9p21 (tagged by the rs1333049 or
rs10757278 single-nucleotide polymorphism) is strongly associated with myocardial …

Endothelial progenitor cell number and colony-forming capacity in overweight and obese adults

OJ MacEneaney, EJ Kushner, GP Van Guilder… - International Journal of …, 2009 - nature.com
Objective: To investigate whether adiposity influences endothelial progenitor cell (EPC)
number and colony-forming capacity. Design: Cross-sectional study of normal weight …

Ex vivo nanofiber expansion and genetic modification of human cord blood-derived progenitor/stem cells enhances vasculogenesis

H Das, N Abdulhameed, M Joseph… - Cell …, 2009 - journals.sagepub.com
The stem cell therapy for treating ischemic diseases is promising; however, the limited
availability and compromised quality of progenitor cells in aged and diseased patients limit …