It is important that the medical profession play a significant role in critically evaluating the
use of diagnostic procedures and therapies as they are introduced and tested in the …

Long-term diabetes increases the likelihood of developing secondary damage to numerous
systems, and these complications represent a substantial cause of morbidity and mortality …

Background Anemia is associated with an increased risk of cardiovascular and renal events
among patients with type 2 diabetes and chronic kidney disease. Although darbepoetin alfa …

GIUSEPPE MANCIAa, STÉPHANE LAURENTb, ENRICO AGABITI-ROSEIc, ETTORE
AMBROSIONId, MICHEL BURNIERe, MARK J. CAULFIELDf, RENATA CIFKOVAg, DENIS …

Diabetes is a chronic illness that re-quires continuing medical care and patient self-
management education to prevent acute complications and to reduce the risk of long-term …

Summary Background Angiotensin-receptor blockers (ARBs) are effective treatments for
patients with heart failure, but the relation between dose and clinical outcomes has not been …

Background Nephropathy and retinopathy remain important complications of type 1
diabetes. It is unclear whether their progression is slowed by early administration of drugs …

Abstract Background and objectives: The Chronic Renal Insufficiency Cohort (CRIC) Study
was established to examine risk factors for the progression of chronic kidney disease (CKD) …

O objetivo desta Diretriz é servir de apoio e auxiliar os médicos nas decisões referentes aos
seus pacientes, elaborando orientações que podem ser úteis na prática médica. A adoção …

Abstract Background. In Fabry disease, progressive glycolipid accumulation leads to organ
damage and early demise, but the incidence of renal, cardiac and cerebrovascular events …