Malaria is a leading cause of mortality and morbidity globally, and effective vaccines are
urgently needed. Malaria vaccine approaches can be broadly grouped as pre‐erythrocytic …

Malaria is a deadly infectious disease that affects one to two billion people and kills up to
one million children yearly. Despite decades of intensive research, we are still lacking an …

Invasion of erythrocytes is a prerequisite in the life history of the malaria parasite. Members
of the reticulocyte-binding homologue family (PfRh) have been implicated in the invasion …

Substantial evidence indicates that antibodies to Plasmodium falciparum merozoite antigens
play a role in protection from malaria, although the precise targets and mechanisms …

Apicomplexa are obligate intracellular parasites that actively invade host cells using their
membrane-associated, actin-myosin motor. The current view is that host cell invasion by …

The role of early to intermediate Plasmodium falciparum-induced cellular responses in the
development of clinical immunity to malaria is not well understood, and such responses …

Individuals repeatedly infected with malaria acquire protection from infection and disease;
immunity is thought to be primarily antibody-mediated and directed to blood-stage infection …

Plasmodium falciparum invasion into human erythrocytes relies on the interaction between
multiple parasite ligands and their respective erythrocyte receptors. The sialic acid …

Egress is a pivotal step in the life cycle of intracellular pathogens initiating the transition from
an expiring host cell to a fresh target cell. While much attention has been focused on …

Apicomplexan parasites employ multiple adhesive ligands for recognition and entry into host
cells. The Duffy binding-like (DBL) and the reticulocyte binding protein-like (RBL) families …