The chemokine receptor CXCR4 belongs to the large superfamily of G-protein-coupled
receptors, and is directly involved in a number of biological processes including …

The association between chronic inflammation and lung cancer has been extensively
reported. Despite the differences in the clinical manifestations of chronic obstructive …

BACKGROUND: The authors elucidated particular chemokine receptors that are expressed
on lung cancer cells, as well as the clinical significance of the expression of these …

OBJECTIVES: Although the chemokine CXCL12 and its receptor CXCR4 have been
implicated in metastasis of non–small cell lung carcinoma, the prognostic significance of …

Chemokines and chemokine receptors have been shown to be involved in metastatic
process of prostate cancer (PCa). In this study, we show primary PCa tissues and cell lines …

Chemokines and their receptors are implicated in formation of colorectal cancer metastases.
Especially CXCR4 is an important factor, determining migration, invasiveness, metastasis …

Chemokines and their receptors seem to act as important regulators of the metastatic
cascade. CXCL12 and its receptor CXCR4 were shown to be involved in human cancer …

The chemokine receptor CXCR4 is involved in the metastasis of many cancers. Recent
evidence suggests that CXCR4 may be also involved in the metastasis of renal cell …

Metastasis is the major cause of mortality in lung cancer. Chemotaxis plays a vital role in
cancer cell metastasis. In the current study, we reported that epidermal growth factor (EGF) …

Purpose: Lymph node metastasis (LNM) is a chief cause of morbidity and mortality in
patients with hepatocellular carcinoma (HCC) after hepatectomy. The aim of this study was …