Regulation of intrinsic excitability in hippocampal neurons by activity-dependent modulation of the KV2.1 potassium channel

DP Mohapatra, H Misonou, P Sheng-Jun, JE Held… - Channels, 2009 - Taylor & Francis
KV2. 1 is the prominent somatodendritic sustained or delayed rectifier voltage-gated
potassium (Kv) channel in mammalian central neurons, and is a target for activity-dependent …

Voltage-gated sodium channel modulation by σ-receptors in cardiac myocytes and heterologous systems

M Johannessen, S Ramachandran… - … of Physiology-Cell …, 2009 - journals.physiology.org
The σ-receptor, a broadly distributed integral membrane protein with a novel structure, is
known to modulate various voltage-gated K+ and Ca2+ channels through a mechanism that …

Kv2.1 and silent Kv subunits underlie the delayed rectifier K+ current in cultured small mouse DRG neurons

E Bocksteins, AL Raes… - … of Physiology-Cell …, 2009 - journals.physiology.org
Silent voltage-gated K+ (Kv) subunits interact with Kv2 subunits and primarily modulate the
voltage dependence of inactivation of these heterotetrameric channels. Both Kv2 and silent …

Zn2+ regulates Kv2.1 voltage‐dependent gating and localization following ischemia

MA Aras, RA Saadi, E Aizenman - European Journal of …, 2009 - Wiley Online Library
The delayed‐rectifier K+ channel Kv2. 1 exists in highly phosphorylated somatodendritic
clusters. Ischemia induces rapid Kv2. 1 dephosphorylation and a dispersal of these clusters …

Rearrangements in the relative orientation of cytoplasmic domains induced by a membrane-anchored protein mediate modulations in Kv channel gating

A Lvov, D Greitzer, S Berlin, D Chikvashvili… - Journal of Biological …, 2009 - ASBMB
Interdomain interactions between intracellular N and C termini have been described for
various K+ channels, including the voltage-gated Kv2. 1, and suggested to affect channel …

The Diverse Roles of K+Channels in Brain Ischemia

H Misonou, JS Trimmer - New Strategies in Stroke Intervention: Ionic …, 2009 - Springer
K+-selective ion channels are important determinants of neuronal excitability. The activity of
three particular K+ channels, Kir6. 2, Slo1, and Kv2. 1, is implicated in neuroprotection of …

Zinc Signaling in Neuronal Tolerance

MA Aras - 2009 - d-scholarship.pitt.edu
Sub-lethal preconditioning stimuli can confer neuronal tolerance by triggering the activation
of endogenous survival pathways that limit or resist subsequent injury. Recent evidence has …

[图书][B] Small conductance calcium-activated potassium (SK) channels in mammalian spinal motoneurons

Z Deng - 2009 - search.proquest.com
Three homologous small conductance calcium-activated potassium (SK) channel subunits
(SK1, SK2 & SK3) are expressed in distinct and overlapping patterns in mammalian central …