Heterogeneity in the natural killer (NK) cell population is determined by variegated
expression of polygenic and polymorphic receptors and distinct phenotypes and functions of …

Armed with potent cytotoxic and immunostimulatory effector functions, natural killer (NK)
cells have the potential to cause significant damage to normal self cells unless controlled by …

Inhibitory receptors that engage self-MHC class I molecules enable NK cells to detect
disease-associated loss of MHC class I on surrounding cells. Previous studies showed that …

Natural killer (NK) cells express inhibitory receptors for major histocompatibility complex
(MHC) class I. If self-MHC is down-regulated or absent, lack of inhibition triggers “missing …

Natural killer (NK) cells show enhanced functional competence when they express inhibitory
receptors specific for inherited major histocompatibility complex class I (MHC-I) molecules …

During the co-evolution of cytomegalovirus (CMV) and natural killer (NK) cells, each has
evolved specific tactics in an attempt to prevail. CMV has evolved multiple immune evasion …

Murine natural killer (NK) cells express inhibitory Ly49 receptors for MHC class I molecules,
which allows for “missing self” recognition of cells that downregulate MHC class I …

NK cells have two main functions, namely cell‐mediated cytotoxicity and production of
cytokines. Multiple inhibitory receptors that regulate NK‐cell cytotoxicity have been …

Successful application of γδ T cells in adoptive cell therapies depends upon our ability to
maintain these cells in vivo. Using an adoptive transfer model to study lymphopenia-induced …

Recent data showing expression of activating NK receptors (NKR) by conventional T
lymphocytes raise the question of their role in the triggering of TCR-independent responses …