Antioxidant therapy in critically septic patients

S Rinaldi, F Landucci, AR De Gaudio - Current drug targets, 2009 - ingentaconnect.com
Critical illness and particularly sepsis are associated with a significant redox imbalance
resulting from an increased production of oxidant species and a decrease in endogenous …

Alcohol abuse and pulmonary disease

DM Boé, RW Vandivier, EL Burnham… - Journal of leukocyte …, 2009 - academic.oup.com
Review on alcohol abuse increasing the risk for acute respiratory distress syndrome through
alterations in pulmonary function, and implications to potential therapeutic targets. ARDS is …

Role of oxidative stress in ultrafine particle–induced exacerbation of allergic lung inflammation

F Alessandrini, I Beck-Speier… - American journal of …, 2009 - atsjournals.org
Rationale: The effects of ultrafine particle inhalation on allergic airway inflammation are of
growing interest. The mechanisms underlying these effects are currently under investigation …

N‐acetylcysteine, a thiol antioxidant, decreases alveolar bone loss in experimental periodontitis in rats

H Toker, H Ozdemir, K Eren, H Ozer… - Journal of …, 2009 - Wiley Online Library
Background: The purpose of this study was to analyze the morphometric and histopathologic
changes associated with experimental periodontitis in rats in response to systemic …

Amifostine reduces lung vascular permeability via suppression of inflammatory signalling

P Fu, AA Birukova, J Xing, S Sammani… - European …, 2009 - Eur Respiratory Soc
Despite an encouraging outcome of antioxidant therapy in animal models of acute lung
injury, effective antioxidant agents for clinical application remain to be developed. The …

[HTML][HTML] Synthetic RGDS peptide attenuates lipopolysaccharide-induced pulmonary inflammation by inhibiting integrin signaled MAP kinase pathways

C Moon, JR Han, HJ Park, JS Hah, JL Kang - Respiratory research, 2009 - Springer
Background Synthetic peptides containing the RGD sequence inhibit integrin-related
functions in different cell systems. Here, we investigated the effects of synthetic Arg-Gly-Asp …

Attenuation of pulmonary inflammation after exposure to blast overpressure by N-acetylcysteine amide

M Chavko, S Adeeb, ST Ahlers, RM McCarron - Shock, 2009 - journals.lww.com
Lung contusion is a common problem from blunt chest trauma caused by mechanical forces
and by exposure to blast overpressure, often with fatal consequences. Lung contusion is …

Naturally occurring antioxidant nutrients reduce inflammatory response in mice

EG Novoselova, SM Lunin, TV Novoselova… - European journal of …, 2009 - Elsevier
The effects of mixed dietary coenzyme Q9, α-tocopherol, and β-carotene on immune cell
activity and blood cytokine profile were studied in peritoneal macrophages, spleen …

Extracellular superoxide dismutase haplotypes are associated with acute lung injury and mortality

JJ Arcaroli, JE Hokanson, E Abraham… - American journal of …, 2009 - atsjournals.org
Rationale: Extracellular superoxide dismutase (EC-SOD) is a potent antioxidant that plays
an important role in controlling oxidant-mediated stress and inflammation. High levels of EC …

The interaction of oxidative stress response with cytokines in the thyrotoxic rat: is there a link?

B Makay, O Makay, C Yenisey, G Icoz… - Mediators of …, 2009 - Wiley Online Library
Oxidative stress is regarded as a pathogenic factor in hyperthyroidism. Our purpose was to
determine the relationship between the oxidative stress and the inflammatory cytokines and …