A multipurpose microfluidic device designed to mimic microenvironment gradients and develop targeted cancer therapeutics
CL Walsh, BM Babin, RW Kasinskas, JA Foster… - Lab on a Chip, 2009 - pubs.rsc.org
The heterogeneity of cellular microenvironments in tumors severely limits the efficacy of
most cancer therapies. We have designed a microfluidic device that mimics the …
most cancer therapies. We have designed a microfluidic device that mimics the …
A quantitative cellular automaton model of in vitro multicellular spheroid tumour growth
MJ Piotrowska, SD Angus - Journal of theoretical biology, 2009 - Elsevier
We report numerical results from a 2D cellular automaton (CA) model describing the
dynamics of the in vitro cultivated multicellular spheroid obtained from EMT6/Ro (mammary …
dynamics of the in vitro cultivated multicellular spheroid obtained from EMT6/Ro (mammary …
In vitro three‐dimensional modelling of human ovarian surface epithelial cells
K Lawrenson, E Benjamin, M Turmaine… - Cell …, 2009 - Wiley Online Library
Objectives: Ninety percent of malignant ovarian cancers are epithelial and thought to arise
from the ovarian surface epithelium (OSE). We hypothesized that biological characteristics of …
from the ovarian surface epithelium (OSE). We hypothesized that biological characteristics of …
[图书][B] Intracellular metabolism of cancer cells and drug delivery using gold nanoparticles in an in vitro 3D tumor model
B Kim - 2009 - search.proquest.com
Heterogeneous tumor microenvironments reduce the efficacy of cancer therapeutics
because associated heterogeneous tumor cell populations respond differently to treatments …
because associated heterogeneous tumor cell populations respond differently to treatments …