Conformational dynamics in the Acyl-CoA synthetases, adenylation domains of non-ribosomal peptide synthetases, and firefly luciferase

AM Gulick - ACS chemical biology, 2009 - ACS Publications
The ANL superfamily of adenylating enzymes contains acyl-and aryl-CoA synthetases, firefly
luciferase, and the adenylation domains of the modular non-ribosomal peptide synthetases …

Recent advances in siderophore biosynthesis

SM Barry, GL Challis - Current Opinion in Chemical Biology, 2009 - Elsevier
The biosynthesis of the microbial small molecule iron scavengers known as siderophores
has been of interest since their discovery in the middle of the past century. Two main …

Three Genomes from the Phylum Acidobacteria Provide Insight into the Lifestyles of These Microorganisms in Soils

NL Ward, JF Challacombe, PH Janssen… - Applied and …, 2009 - Am Soc Microbiol
The complete genomes of three strains from the phylum Acidobacteria were compared.
Phylogenetic analysis placed them as a unique phylum. They share genomic traits with …

The role of siderophores in iron acquisition by photosynthetic marine microorganisms

BM Hopkinson, FMM Morel - Biometals, 2009 - Springer
The photosynthetic picocyanobacteria and eukaryotic microorganisms that inhabit the open
ocean must be able to supply iron for their photosynthetic and respiratory needs from the …

Characterization of staphyloferrin A biosynthetic and transport mutants in Staphylococcus aureus

FC Beasley, ED Vinés, JC Grigg, Q Zheng… - Molecular …, 2009 - Wiley Online Library
Iron is critical for virtually all forms of life. The production of high‐affinity iron chelators,
siderophores, and the subsequent uptake of iron–siderophore complexes are a common …

Molecular characterization of staphyloferrin B biosynthesis in Staphylococcus aureus

J Cheung, FC Beasley, S Liu, GA Lajoie… - Molecular …, 2009 - Wiley Online Library
Siderophores are iron‐scavenging molecules produced by many microbes. In general, they
are synthesized using either non‐ribosomal peptide synthetase (NRPS) or NRPS …

The long-overlooked enzymology of a nonribosomal peptide synthetase-independent pathway for virulence-conferring siderophore biosynthesis

D Oves-Costales, N Kadi, GL Challis - Chemical communications, 2009 - pubs.rsc.org
Siderophores are high-affinity ferric iron chelators biosynthesised and excreted by most
microorganisms that play an important role in iron acquisition. Siderophore-mediated …

[HTML][HTML] Amidoligases with ATP-grasp, glutamine synthetase-like and acetyltransferase-like domains: synthesis of novel metabolites and peptide modifications of …

LM Iyer, S Abhiman, AM Burroughs, L Aravind - Molecular bioSystems, 2009 - pubs.rsc.org
Recent studies have shown that the ubiquitin system had its origins in ancient
cofactor/amino acid biosynthesis pathways. Preliminary studies also indicated that …

Analysis of Achromobactin Biosynthesis by Pseudomonas syringae pv. syringae B728a

AD Berti, MG Thomas - Journal of bacteriology, 2009 - Am Soc Microbiol
Pseudomonas syringae pv. syringae B728a is known to produce the siderophore
pyoverdine under iron-limited conditions. It has also been proposed that this pathovar has …

Identification and Characterization of the Staphylococcus aureus Gene Cluster Coding for Staphyloferrin A

JL Cotton, J Tao, CJ Balibar - Biochemistry, 2009 - ACS Publications
Siderophores are key virulence factors that allow bacteria to grow in iron-restricted
environments. The Gram-positive pathogen Staphylococcus aureus is known to produce …