Objective To examine the use of qualitative approaches alongside randomised trials of
complex healthcare interventions. Design Review of randomised controlled trials of …

Randomised evaluations of surgical interventions are rare; some interventions have been
widely adopted without rigorous evaluation. Unlike other medical areas, the randomised …

Objective To quantify the risk and severity of negative effects of treatment for localised
prostate cancer on long term quality of life. Design Population based, prospective cohort …

Objective To explore expectations and experiences of online cognitive behavioural therapy
(CBT) among primary‐care patients with depression, focusing on how this mode of delivery …

CONTEXT: Due to early detection strategies, prostate cancer is diagnosed early in its natural
history. It remains unclear whether all patients diagnosed with prostate cancer warrant …

Background. Recruitment to health research is known to be problematic. However, evidence
concerning ways of improving recruitment is sparse. Objective. To outline the process of …

Mixed methods research is undertaken in a wide range of fields, such as education,
psychology, social sciences, and health sciences. The acceptance of this approach, levels of …

Randomised controlled trials (RCTs) represent the gold standard methodology for
determining effectiveness of healthcare interventions. Poor recruitment to RCTs can threaten …

In health sciences research, significant methodological diversity of clinical research has
occurred during the past two decades (Stange et al. 2006). Indeed, Borkan (2004) considers …

BACKGROUND: Under-recruitment to randomised controlled trials (RCTs) is often
problematic and there may be particular difficulties in recruiting patients with severe mental …