How I treat symptomatic splenomegaly in patients with myelofibrosis

RA Mesa - Blood, The Journal of the American Society of …, 2009 - ashpublications.org
Managing patients with myelofibrosis (MF), either those with primary MF or those whose MF
has evolved from antecedent polycythemia vera or essential thrombocythemia, presents …

Conventional cytogenetics in myelofibrosis: literature review and discussion

K Hussein, DL Van Dyke… - European journal of …, 2009 - Wiley Online Library
The clinical phenotype of myelofibrosis (MF) is recognized either de novo (primary) or in the
setting of polycythemia vera (post‐PV) or essential thrombocythemia (post‐ET) …

Primary myelofibrosis: update on definition, pathogenesis, and treatment

OI Abdel-Wahab, RL Levine - Annual review of medicine, 2009 - annualreviews.org
Primary myelofibrosis (PMF) is a clonal stem cell disorder that manifests clinically as
anemia, splenomegaly due to extramedullary hematopoiesis, leukoerythroblastosis, and …

AML transformation in 56 patients with Ph− MPD in two well defined populations

K Abdulkarim, F Girodon, P Johansson… - European journal of …, 2009 - Wiley Online Library
Abstract The Philadelphia chromosome‐negative (Ph−) chronic myeloproliferative disorders
(MPD) have an inherent tendency for transformation into acute myelogenous leukaemia …

AML1/RUNX1 point mutation possibly promotes leukemic transformation in myeloproliferative neoplasms

Y Ding, Y Harada, J Imagawa… - Blood, The Journal of …, 2009 - ashpublications.org
Myeloproliferative neoplasms (MPNs) are clonal hematopoietic stem cell disorders
characterized by proliferation of one or more myeloid cell lineages. Some patients exhibit …

Emerging drugs for the therapy of primary and post essential thrombocythemia, post polycythemia vera myelofibrosis

RA Mesa, A Tefferi - Expert opinion on emerging drugs, 2009 - Taylor & Francis
Managing patients with myelofibrosis (MF)(both those with primary myelofibrosis or having
evolved from an antecedent polycythemia vera or essential thrombocythemia) present many …

Blast phase of essential thrombocythemia: A single center study

F Passamonti, E Rumi, L Arcaini… - American journal of …, 2009 - Wiley Online Library
Blast phase (BP) may occur as a late event in essential thrombocythemia (ET). This study
includes 19patients with post-ET BP diagnosed and followed in a single institution. At BP …

Mature survival data for 176 patients younger than 60 years with primary myelofibrosis diagnosed between 1976 and 2005: evidence for survival gains in recent years

R Vaidya, S Siragusa, J Huang, SM Schwager… - Mayo Clinic …, 2009 - Elsevier
In the past 20 years, management of primary myelofibrosis (PMF) has incorporated new
treatment approaches, but survival benefits have not been confirmed in controlled studies …

Primary myelofibrosis with concurrent precursor T-cell lymphoblastic lymphoma of the spleen in a 26-year-old patient

M Sever, JL Jorgensen, I Gurevich, M Pinheiro… - Leukemia research, 2009 - Elsevier
Discussion PMF is very rare hematologic neoplasm in young patients. The patient described
here presented with a short history of constitutional symptoms and symptoms related to …