In essentially every domain of neuroscience, the generally implicit assumption that few, if
any, meaningful differences exist between male and female brain function is being …

Adult neurogenesis exists in most mammalian species, including humans, in two main
areas: the subventricular zone (new cells migrate to the olfactory bulbs) and the dentate …

Estrogen, in addition to its genomic effects in brain, causes rapid and reversible changes to
synaptic operations. We report here that these acute actions are due to selective activation …

The question of whether ovarian hormone therapy can prevent or reduce age-related
memory decline in menopausal women has been the subject of much recent debate …

17β-Estradiol (E2) may influence cognitive and/or affective behavior in part via the β isoform
of the estrogen receptor (ERβ). Endocrine status and behavior in cognitive (object …

Decline in the ovarian steroid, estradiol (E2), with the menopause transition may influence
cognitive and affective processing of older women and there is evidence that hormone …

Changes in hippocampal CA1 dendritic spine density and synaptic number across the
estrous cycle in female rats correlate with increased hippocampal-dependent cognitive …

Oestrogens are known to exert significant structural and functional effects in the
hippocampus of adult rodents. The dentate gyrus of the hippocampus retains the ability to …

Extracellular acetylcholine (ACh) levels in the dorsal hippocampus increases during
learning or exploration, exhibiting a sex-specific 24 h release profile. To examine the …

Conjugated equine estrogen (CEE) is the most commonly prescribed estrogen therapy, and
is the estrogen used in the Women's Health Initiative study. While in-vitro studies suggest …