The hypothesis proposed is that heart failure (HF) is associated with a reactive
hyperadrenergic state that increases circulating plasma free fatty acids (FFAs), which leads …

Adiponectin is a protein secreted by adipose cells that may couple regulation of insulin
sensitivity with energy metabolism and serve to link obesity with insulin resistance. Obesity …

BACKGROUND AND AIM: Insulin resistance is recognized as the pathophysiological
hallmark of non-alcoholic fatty liver disease (NAFLD). A relation between insulin sensitivity …

Endocannabinoids are endogenous bioactive lipid mediators present both in the brain and
various peripheral tissues, which exert their biological effects via interaction with specific G …

BACKGROUND: Lipophilic and hydrophilic statins have different effects on adiponectin and
insulin resistance in experimental studies and different effects on the rate of onset of new …

Heme oxygenase (HO) plays a critical role in attenuating the production of reactive oxygen
species through its ability to degrade heme in an enzymatic process that leads to the …

We examined mechanisms by which L-4F reduces obesity and diabetes in obese (ob)
diabetic mice. We hypothesized that L-4F reduces adiposity via increased pAMPK, pAKT …

Chronic inflammation is a pathogenic feature of atherosclerosis and cardiovascular disease
mediated by substances including angiotensin II, proinflammatory cytokines, and free fatty …

Heme oxygenase (HO) is important in attenuating the overall production of reactive oxygen
species through its ability to degrade heme and to produce carbon monoxide …

Background Obesity hypoventilation syndrome (OHS) is associated with increased
cardiovascular morbidity. What moderate chronic hypoventilation adds to obesity on …