Folate-targeted therapeutic and imaging agents for cancer
PS Low, SA Kularatne - Current opinion in chemical biology, 2009 - Elsevier
Cancer therapies that exploit targeting ligands to deliver attached cytotoxic drugs selectively
to malignant cells are currently receiving significant attention. While antibody-targeted drugs …
to malignant cells are currently receiving significant attention. While antibody-targeted drugs …
Multifunctional and stimuli-sensitive pharmaceutical nanocarriers
V Torchilin - European Journal of Pharmaceutics and …, 2009 - Elsevier
Currently used pharmaceutical nanocarriers, such as liposomes, micelles, and polymeric
nanoparticles, demonstrate a broad variety of useful properties, such as longevity in the …
nanoparticles, demonstrate a broad variety of useful properties, such as longevity in the …
Gold Nanorods as Contrast Agents for Biological Imaging: Optical Properties, Surface Conjugation and Photothermal Effects†
Gold nanorods (NRs) have plasmon‐resonant absorption and scattering in the near‐infrared
(NIR) region, making them attractive probes for in vitro and in vivo imaging. In the cellular …
(NIR) region, making them attractive probes for in vitro and in vivo imaging. In the cellular …
Dendrimers in oncology: an expanding horizon
Cancer is a killer disease second only to heart problems. 1 Though there is significant
progress in the field of anticancer technology, we are still badly in need of a reliable cure for …
progress in the field of anticancer technology, we are still badly in need of a reliable cure for …
Targeting and imaging cancer cells by folate-decorated, quantum dots (QDs)-loaded nanoparticles of biodegradable polymers
We developed a new strategy to prepare folate-decorated nanoparticles of biodegradable
polymers for Quantum dots (QDs) formulation for targeted and sustained imaging for cancer …
polymers for Quantum dots (QDs) formulation for targeted and sustained imaging for cancer …
Dendrimer-based nanoparticles for cancer therapy
JR Baker Jr - ASH Education Program Book, 2009 - ashpublications.org
Recent work has suggested that nanoparticles in the form of dendrimers may be a keystone
in the future of therapeutics. The field of oncology could soon be revolutionized by novel …
in the future of therapeutics. The field of oncology could soon be revolutionized by novel …
Dendrimers and nanomedicine: multivalency in action
O Rolland, CO Turrin, AM Caminade… - New Journal of …, 2009 - pubs.rsc.org
What is the contribution of dendrimers to the field of nanomedicine? Rather than disclosing
an exhaustive catalogue of their possible applications, this review article sets a putative …
an exhaustive catalogue of their possible applications, this review article sets a putative …
Bio-conjugated luminescent quantum dots of doped ZnS: a cyto-friendly system for targeted cancer imaging
K Manzoor, S Johny, D Thomas, S Setua… - …, 2009 - iopscience.iop.org
A heavy-metal-free luminescent quantum dot (QD) based on doped zinc sulfide (ZnS),
conjugated with a cancer-targeting ligand, folic acid (FA), is presented as a promising bio …
conjugated with a cancer-targeting ligand, folic acid (FA), is presented as a promising bio …
Oligomeric compounds for the modulation of Bcl-2
M Frieden, JB Hansen, H Orum, M Westergaard… - US Patent …, 2009 - Google Patents
The present invention provides improved oligomeric com pound, in particular
oligonucleotide compounds, and meth ods for modulating the expression of the Bcl-2 gene …
oligonucleotide compounds, and meth ods for modulating the expression of the Bcl-2 gene …
Biotinylated poly (amido) amine (PAMAM) dendrimers as carriers for drug delivery to ovarian cancer cells in vitro
VK Yellepeddi, A Kumar, S Palakurthi - Anticancer research, 2009 - ar.iiarjournals.org
Background: Biotin is an essential micronutrient and its levels are high in rapidly
proliferating cells such as cancer cells. We hypothesized that the synthesis of poly (amido) …
proliferating cells such as cancer cells. We hypothesized that the synthesis of poly (amido) …