An official American Thoracic Society/European Respiratory Society statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials …
HK Reddel, DR Taylor, ED Bateman… - American journal of …, 2009 - atsjournals.org
Background: The assessment of asthma control is pivotal to the evaluation of treatment
response in individuals and in clinical trials. Previously, asthma control, severity, and …
response in individuals and in clinical trials. Previously, asthma control, severity, and …
Comparison of inhaled corticosteroids: an update
HW Kelly - Annals of Pharmacotherapy, 2009 - journals.sagepub.com
Objective: To review the basis for the estimated comparative daily dosages of inhaled
corticosteroids for children and adults that are presented in the National Heart, Lung, and …
corticosteroids for children and adults that are presented in the National Heart, Lung, and …
Inhaled corticosteroids and asthma control in children: assessing impairment and risk
G Rachelefsky - Pediatrics, 2009 - publications.aap.org
OBJECTIVE. To review the use of inhaled corticosteroids on asthma control in children by
using the new therapeutic paradigm outlined in the Expert Panel Report 3: Guidelines for the …
using the new therapeutic paradigm outlined in the Expert Panel Report 3: Guidelines for the …
Total IgE levels and asthma prevalence in the US population: results from the National Health and Nutrition Examination Survey 2005-2006
PJ Gergen, SJ Arbes Jr, A Calatroni, HE Mitchell… - Journal of Allergy and …, 2009 - Elsevier
BACKGROUND: The inability to measure IgE-based sensitivity to all allergens has limited
our understanding of what portion of asthma is related to IgE. Total IgE measurement can …
our understanding of what portion of asthma is related to IgE. Total IgE measurement can …
Body mass index and phenotype in subjects with mild-to-moderate persistent asthma
ER Sutherland, EB Lehman, M Teodorescu… - Journal of Allergy and …, 2009 - Elsevier
BACKGROUND: Although obesity has been hypothesized to worsen asthma, data from
studies of subjects with well-characterized asthma are lacking. OBJECTIVE: We sought to …
studies of subjects with well-characterized asthma are lacking. OBJECTIVE: We sought to …
Predictors of poor response during asthma therapy differ with definition of outcome
AJ Rogers, KG Tantisira, AL Fuhlbrigge… - …, 2009 - Future Medicine
Aims: To evaluate phenotypic and genetic variables associated with a poor long-term
response to inhaled corticosteroid therapy for asthma, based independently on lung function …
response to inhaled corticosteroid therapy for asthma, based independently on lung function …
The irreversible component of persistent asthma
RM Pascual, SP Peters - Journal of allergy and clinical immunology, 2009 - Elsevier
Irreversible airflow obstruction or limitation occurs in some patients with asthma, can
develop early in life, and becomes more common as asthma becomes more severe. Efforts …
develop early in life, and becomes more common as asthma becomes more severe. Efforts …
Prescribing trends in asthma: a longitudinal observational study
S Turner, M Thomas, J von Ziegenweidt… - Archives of disease in …, 2009 - adc.bmj.com
Background: Inhaled corticosteroids (ICS) are effective treatment for childhood asthma.
Cross-sectional studies indicate that some asthmatic children are treated with excessively …
Cross-sectional studies indicate that some asthmatic children are treated with excessively …
Pharmacogenetic study of the effects of NK2R G231E G> A and TBX21 H33Q C> G polymorphisms on asthma control with inhaled corticosteroid treatment
Summary Background and Objective: Inhaled corticosteroids (ICS) are widely used as
maintenance regimens for asthma patients. However, response to ICS shows marked inter …
maintenance regimens for asthma patients. However, response to ICS shows marked inter …
[HTML][HTML] Importin-13 genetic variation is associated with improved airway responsiveness in childhood asthma
Background Glucocorticoid function is dependent on efficient translocation of the
glucocorticoid receptor (GR) from the cytoplasm to the nucleus of cells. Importin-13 (IPO13) …
glucocorticoid receptor (GR) from the cytoplasm to the nucleus of cells. Importin-13 (IPO13) …