Efficacy and safety of intermittent preventive treatment with sulfadoxine-pyrimethamine for malaria in African infants: a pooled analysis of six randomised, placebo …

JJ Aponte, D Schellenberg, A Egan, A Breckenridge… - The Lancet, 2009 - thelancet.com
Background Intermittent preventive treatment (IPT) is a promising strategy for malaria control
in infants. We undertook a pooled analysis of the safety and efficacy of IPT in infants (IPTi) …

Loss of population levels of immunity to malaria as a result of exposure-reducing interventions: consequences for interpretation of disease trends

AC Ghani, CJ Sutherland, EM Riley, CJ Drakeley… - PloS one, 2009 - journals.plos.org
Background The persistence of malaria as an endemic infection and one of the major
causes of childhood death in most parts of Africa has lead to a radical new call for a global …

Protective efficacy and safety of three antimalarial regimens for intermittent preventive treatment for malaria in infants: a randomised, double-blind, placebo-controlled …

RD Gosling, S Gesase, JF Mosha, I Carneiro… - The Lancet, 2009 - thelancet.com
Background Administration of sulfadoxine-pyrimethamine at times of vaccination—
intermittent preventive treatment in infants (IPTi)—is a promising strategy to prevent malaria …

A randomized trial assessing the safety and immunogenicity of AS01 and AS02 adjuvanted RTS, S malaria vaccine candidates in children in Gabon

B Lell, S Agnandji, I Von Glasenapp, S Haertle… - PLoS one, 2009 - journals.plos.org
Background The malaria vaccine candidate antigen RTS, S includes parts of the pre-
erythrocytic stage circumsporozoite protein fused to the Hepatitis B surface antigen. Two …

A simple method for defining malaria seasonality

A Roca-Feltrer, JRMA Schellenberg, L Smith… - Malaria journal, 2009 - Springer
Background There is currently no standard way of defining malaria seasonality, resulting in
a wide range of definitions reported in the literature. Malaria cases show seasonal peaks in …

Reasons for non-adherence to vaccination at mother and child care clinics (MCCs) in Lambarene, Gabon

NG Schwarz, M Gysels, C Pell, J Gabor, M Schlie… - Vaccine, 2009 - Elsevier
The aim of this paper is to explore attitudes of mothers towards childhood vaccinations and
reasons for non-attendance and non-adherence to mother–child clinics (MCCs). Forty in …

[PDF][PDF] Cost-effectiveness of malaria intermittent preventive treatment in infants (IPTi) in Mozambique and the United Republic of Tanzania

G Hutton, D Schellenberg, F Tediosi… - Bulletin of the World …, 2009 - SciELO Public Health
OBJECTIVE: To estimate the cost-effectiveness of malaria intermittent preventive treatment
in infants (IPTi) using sulfadoxine-pyrimethamine (SP). METHODS: In two previous IPTi trials …

Community response to intermittent preventive treatment of malaria in infants (IPTi) delivered through the expanded programme of immunization in five African settings

M Gysels, C Pell, DP Mathanga, P Adongo… - Malaria Journal, 2009 - Springer
Background IPTi delivered through EPI has been shown to reduce the incidence of clinical
malaria by 20–59%. However, new health interventions can only be effective if they are also …

Intermittent preventive treatment of malaria in infants: how does it work and where will it work?

RD Gosling, I Carneiro… - Tropical Medicine & …, 2009 - Wiley Online Library
We discuss the potential public health impact of IPTi by estimating the cases of malaria,
anaemia and hospital admissions likely to be averted in different transmission settings; and …

Reduced efficacy of intermittent preventive treatment of malaria in malnourished children

I Danquah, E Dietz, P Zanger, K Reither… - Antimicrobial agents …, 2009 - Am Soc Microbiol
Intermittent preventive treatment in infants with sulfadoxine-pyrimethamine (IPTi-SP)
reduces malaria episodes by 20 to 59% across Africa. This protective efficacy, however, may …