The interaction of mammalian cells with nanoscale topography has proven to be an
important signaling modality in controlling cell function. Naturally occurring nanotopographic …

The field of tissue engineering places complex demands on the materials it uses. The
materials chosen to support the intricate processes of tissue development and maintenance …

Neural tissue repair and regeneration strategies have received a great deal of attention
because it directly affects the quality of the patient's life. There are many scientific challenges …

During the progression of metastasis, cancer cells detach from the solid primary tumor, enter
the blood stream, and travel to different tissues of the body. These breakaway cancer cells in …

Most tissue cells grown in sparse cultures on linearly elastic substrates typically display a
small, round phenotype on soft substrates and become increasingly spread as the modulus …

Mechanical forces play important roles in the regulation of various biological processes at
the molecular and cellular level, such as gene expression, adhesion, migration, and cell …

In this report, we describe using ultraviolet (UV)-assisted capillary force lithography (CFL) to
create a model substratum of anisotropic micro-and nanotopographic pattern arrays with …

In this study we investigate the effects of nanotubular titanium oxide (TiO2) surfaces on
vascular cells. EC and VSMC response to nanotubes was investigated through …

This work reports the design of and experimentation with a topographically patterned cell
culture substrate of variable local density and anisotropy as a facile and efficient platform to …

Influencing cell behavior from proliferation to differentiation using substrate or implant
topography is an attractive strategy for regenerative medicine applications. Substrate …