Investigating proteins 'at work'in a living environment at atomic resolution is a major goal of
molecular biology, which has not been achieved even though methods for the three …

Pseudomonas aeruginosa isolates have a highly conserved core genome representing up
to 90% of the total genomic sequence with additional variable accessory genes, many of …

The difficulty associated with the cultivation of most microorganisms and the complexity of
natural microbial assemblages, such as marine plankton or human microbiome, hinder …

The initial outcome of genome sequencing is the creation of long text strings written in a four
letter alphabet. The role of in silico sequence analysis is to assist biologists in the act of …

ABSTRACT The 6.10-Mb genome sequence of the aerobic chitin-digesting gliding
bacterium Flavobacterium johnsoniae (phylum Bacteroidetes) is presented. F. johnsoniae is …

Background Microbes engage in a remarkable array of cooperative behaviors, secreting
shared proteins that are essential for foraging, shelter, microbial warfare, and virulence …

Background Edwardsiella tarda is the etiologic agent of edwardsiellosis, a devastating fish
disease prevailing in worldwide aquaculture industries. Here we describe the complete …

Pseudomonas aeruginosa is a well-studied opportunistic pathogen that is particularly known
for its intrinsic antimicrobial resistance, diverse metabolic capacity, and its ability to cause …

Background Antibiotic exposure rapidly selects for more resistant bacterial strains, and both
a drug's chemical structure and a bacterium's cellular network affect the types of mutations …

Background It has been noted that many bacterial virulence factor genes are located within
genomic islands (GIs; clusters of genes in a prokaryotic genome of probable horizontal …