Nuclear factor‐kappaB (NF‐κB) is a dimeric transcription factor composed of five members,
p50, RelA/p65, c‐Rel, RelB, and p52 that can diversely combine to form the active …

Our laboratories have previously identified the α7 nAChR–JAK2 pathway as playing a
central role in nicotine-induced neuroprotection. We have also reported that the angiotensin …

Diverse nuclear factor‐κB subunits mediate opposite effects of extracellular signals on
neuron survival. While RelA is activated by neurotoxic agents, c‐Rel drives neuroprotective …

Methylprednisolone (MP), a synthetic glucocorticoid agonist, is widely used for the clinical
therapy of white matter diseases in the nervous system, such as spinal cord injury and …

Dexamethasone (DX) induces apoptosis resistance in most solid malignant tumors during
co-treatment with chemotherapy agents, such as camptothecin (CAM). In this study, we …

Smooth muscle cells (SMCs) undergo changes related to proliferation and apoptosis in the
physiological remodeling of vessels and in diseases such as atherosclerosis and restenosis …

Bcl-xl and the hepatocyte growth factor (HGF) receptor c-Met are both highly expressed in
mesotheliomas, where they protect cells from apoptosis and can confer resistance to …

The NF‐κB signalling pathway plays important roles in liver organogenesis and
carcinogenesis. Mouse embryos deficient in IKKβ die in mid‐gestation, due to excessive …

Smooth muscle cells (SMCs) undergo changes related to proliferation and apoptosis in the
physiological remodeling of vessels and in diseases such as atherosclerosis and restenosis …

The dedifferentiation and proliferation/apoptosis of smooth muscle cells (SMCs) in the
arterial intima represent one of the changes found in early atherosclerotic lesions, when the …